Tag: Prostate Cancer

A new review proposes an anatomy-guided framework in which the bladder, prostate and kidney each demand distinct nanomedicine designs to ...

Circular RNA circLPAR3 blocks ferroptosis to fuel chemotherapy resistance in prostate cancer

Researchers at Nanjing Medical University report that the m6A-stabilized circular RNA circLPAR3 suppresses ferroptosis through the PCBP2/CHAC1 axis, driving docetaxel ...

Old Antibiotics, New Trick: Doxycycline Blocks Prostate Cancer Spread to Bone

Researchers report that the FDA-approved antibiotics doxycycline and methacycline selectively bind acetylated KLF5 and suppress prostate cancer bone metastasis by ...

Simple Blood Test Clue Helps Predict Bone Metastasis in New Prostate Cancer Cases

Chinese researchers have developed and externally validated a prediction model combining PSA, tumor stage, biopsy grade, and the neutrophil-to-lymphocyte ratio ...

Bacterial Signatures in Prostate Tissue Linked to Cancer in Landmark French Study

A multicenter French study using full-length 16S rDNA sequencing found that men with prostate cancer harbor a more diverse prostate ...

AI Fuses PET and MRI Scans to Predict Prostate Cancer Aggressiveness Before Surgery

A new study shows that an interpretable AI model fusing 18F-PSMA-1007 PET/CT and multiparametric MRI can predict prostate cancer aggressiveness ...

When Patients Can’t Pay, Surgeons Steer Away From Expensive Robots, Study Finds

A national discrete choice experiment of 211 Chinese urologists found that surgeons' stated preferences for robot-assisted versus laparoscopic prostatectomy shifted ...

Single tRNA Molecule Found to Steer Prostate Cancer Between Drug Sensitivity and Resistance

Fred Hutch researchers report in Nature that a single transfer RNA, tRNA1Arg(UCU), controls whether prostate cancer cells remain androgen receptor-dependent ...

Doctors Rethink How Autistic Patients Weigh Life-or-Death Cancer Choices

A new case report in the Journal of General Internal Medicine shows how clinicians can support autistic and neurodivergent patients ...

Hidden Prostate Cancer Patterns That Predict Deadly Disease Are Being Missed in Biopsies

A new Nature Reviews Urology review warns that intraductal and invasive cribriform prostate cancers are aggressive, genomically unstable and frequently ...

Nuclear Medicine Advances Span Prostate Cancer, Stroke, and Diabetes Imaging

New ahead-of-print studies in The Journal of Nuclear Medicine describe advances in prostate cancer theranostics, enzyme-enhanced tumor imaging, novel PET ...

Cholesterol’s Hidden Geography: How Tumor Neighborhoods Fuel Resistant Prostate Cancer

A paired spatial multi-omics study of prostate cancer reveals that rising cholesterol during therapy tracks with castration resistance, as import-dominant ...

Proteomics and machine learning expose hidden toxicity in protein degrader drugs

High-throughput proteomics and machine learning revealed that cereblon-recruiting androgen receptor degraders inhibit mitochondrial complex I, and guided linker modifications that ...

A Single tRNA Molecule Controls Whether Prostate Cancer Stays Vulnerable to Therapy

A new Nature study shows that the dosage of a single transfer RNA, tRNA1Arg(UCU), acts as a reversible molecular switch ...

Hidden Aggression: Machine Learning Exposes Dangerous Biology in Low-Risk Prostate Cancer

Researchers at KTH Royal Institute of Technology used multi-omics analysis and machine learning to uncover molecular features linked to aggressive ...

Sharper Prostate MRI Scans May Not Mean Better Cancer Detection, Review Finds

A systematic review of eight studies finds that higher prostate MRI quality shows inconsistent and very-low-certainty associations with the confirmation ...

PSMA PET/CT Outperforms Bone Scans for Prostate Cancer Spread, Threshold Study Finds

A head-to-head study of 108 prostate cancer patients shows gallium-68 PSMA PET/CT detects bone metastases far more accurately than conventional ...

Theranostics Comes of Age: New Supplement Maps the Field’s Next Decade