Researchers have introduced KlaDB, an open-access database compiling 64,072 experimentally identified lysine lactylation sites across nine species alongside standardized prediction ...
A new review synthesizes how phosphorylation, ubiquitination, methylation, SUMOylation and O-GlcNAcylation form an interconnected network that controls the mitotic kinase ...
A new review maps how metabolite-driven protein modifications such as lactylation, O-GlcNAcylation and succinylation may link the disc's harsh metabolic ...
A review in Acta Neuropathologica Communications describes how aberrant liquid-liquid phase separation may drive glioblastoma progression and therapy resistance, and ...
A review finds that protein modifications regulate immune inflammation and epithelial barrier dysfunction in ulcerative colitis through mechanisms that remain ...
A new review reveals how the tumor suppressor and deubiquitinating enzyme CYLD is switched on and off by phosphorylation, ubiquitination, ...
A new BMC Medicine review maps how post-translational modifications act as a networked control layer that gates, amplifies, and dampens ...
A new review in Advanced Cancer Research details how post-translational modifications regulate KRAS localization, activity, stability, and degradation, opening fresh ...
A new review in the Journal of Translational Medicine reframes tau phosphorylation as a dynamic hub within a multi-scale network ...
Researchers have developed an electroporation-based NMR method that delivers labeled proteins into intact mitochondria, enabling atomic-resolution observation of alpha-synuclein membrane ...
Recent advancements in bioinformatics have led to the development of innovative models aimed at enhancing our understanding of post-translational modifications ...
In a groundbreaking study that could transform our understanding of metabolic liver diseases, researchers have unveiled a novel biochemical modification ...
