Human-on-a-chip model tests cancer drug efficacy and toxicity for therapeutic index
In vitro multi-organ system by Hesperos, Inc. realistically replicates the responses of cancer treatments and has potential to inform treatment ...
Tag: Pharmaceutical Sciences
Mapping and measuring proteins on the surfaces of endoplasmic reticulum (ER) in cells
Credit: Kanazawa University Sigma receptors are proteins found on mainly the surface of endoplasmic reticulum (ER) in certain cells. Sigma-1 ...
Exploring new ways to treat different cancers
This eBook is edited by Dr.Atta-ur-Rahman and Dr. M. Iqbal Choudhary, published on May 31, 2019. Bentham Science's premier Anti-cancer ...
Colorado enrolls first patient in clinical trial of HDAC inhibitor, OKI-179
Credit: University of Colorado Cancer Center OnKure, Inc. and the University of Colorado Cancer Center today announced enrollment of the ...
Dundee lab solves HOIL-1 mystery
The mysterious function of a key protein has been revealed following a breakthrough by University of Dundee scientists The mysterious ...
Stem cells reprogrammed into neurons could reveal drugs harmful to pregnancy
A tool for probing genetic and molecular underpinnings of drug-induced neurodevelopmental disordersCredit: Soham Chanda/Colorado State University Pregnant women are often ...
Harvard chemists’ breakthrough in synthesis advances a potent anti-cancer agent
'Unprecedented achievement' provides sufficient quantities of a fully synthetic halichondrin molecule for clinical trials now underway It's a feat three ...
Researchers’ discovery could lead to improved therapies for duchenne muscular dystrophy
Credit: Parvatiyar A new multi-institution study spearheaded by researchers at Florida State University and the University of California, Los Angeles ...
A rapid, easy-to-use DNA amplification method at 37°C
Study could advance molecular diagnosis and roboticsCredit: Organic and Biomolecular Chemistry Scientists in Japan have developed a way of amplifying ...
A homing beacon for chemotherapy drugs
Credit: Adapted from ACS Central Science 2019, DOI: 10.1021/acscentsci.9b00195 Killing tumor cells while sparing their normal counterparts is a central ...
Community pharmacies make a lifestyle impact for patients with prostate cancer
Cardiovascular health and physical activity levels of prostate cancer patients improve following successful interventions by community pharmacies, new research in ...
Cause of hardening of the arteries — and potential treatment — identified
Credit: Melinda Duer/Cathy Shanahan A team of UK scientists have identified the mechanism behind hardening of the arteries, and shown ...
Boehringer Ingelheim and University of Dundee extend PROTAC Drug Discovery Program
Boehringer Ingelheim and Dundee extend ongoing anti-cancer alliance Boehringer Ingelheim and University of Dundee achieve milestone in collaboration aimed at ...
Learning from nature’s bounty: New libraries for drug discovery
Credit: Image: University of Basel, Basilius Sauter | CC BY-SA 3.0 Natural products, or their close derivatives, make some of ...
Stanford researchers synthesize healing compounds in scorpion venom
Credit: Edson N. Carcamo-Noriega A scorpion native to Eastern Mexico may have more than just toxin in its sting. Researchers ...
ORNL welcomes seven new research fellows to Innovation Crossroads
Credit: Carlos Jones/Oak Ridge National Laboratory, US Dept. of Energy OAK RIDGE, Tenn., June 10, 2019--Oak Ridge National Laboratory welcomed ...
Study finds FDA dermatology advisors receive payments following drug approvals
Fifty-four percent received at least one payment from pharmaceutical companies A team of researchers led by a member of the ...
Sun-exposed oyster mushrooms help patients fight tuberculosis
Bread containing the low-cost mushrooms increased vitamin D levels and boosted immune response of TB patients Baltimore (June 9, 2019) ...
Researchers develop fast, efficient way to build amino acid chains
Credit: Photo by L. Brian Stauffer CHAMPAIGN, Ill. -- Scientists often build new protein molecules by stringing groups of amino ...
New synthesis of complex organic molecules revealed
Researchers design sequential sequence to fabricate cyclic organic compoundsCredit: FIGURE ADAPTED WITH PERMISSION FROM Org. Lett. 2019, 21, 2383?2387. COPYRIGHT ...
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