Researchers engineered a synthetic bone marrow hydrogel organoid showing that leukaemia cells form protective tunnelling nanotube connections to stroma during ...
Integrated single-cell and spatial transcriptomics reveal that recurrent hypopharyngeal squamous cell carcinoma undergoes cellular reprogramming driven by an IGF2BP2-SMAD3 axis, ...
Researchers found that bile acid stress drives the transcription factor TFAP2A to stabilize Golgi protein GOLIM4 in the cytoplasm, alleviating ...
Two patient-derived pancreatic cancer xenografts produced contrasting wasting phenotypes in mice, with higher tumor P2RY2 and lower ASS1 expression linked ...
A screen of over 1400 FDA-approved compounds identified topoisomerase I inhibitors as the most effective partners for PARP inhibitors in ...
Adapting to serine and glycine scarcity rewires mitochondrial metabolism in pancreatic cancer cells and increases their cancer stem cell frequency, ...
A Nature Communications study shows that loss of the SWI/SNF subunit SMARCD1 drives clear cell renal cell carcinoma through a ...
A team at Nanjing Medical University used RFdiffusion to design a CLDN18.2-targeting T-cell engager for gastric cancer and showed that ...
St. Jude scientists and collaborators built a comprehensive single-cell dataset and patient-derived models to identify a malignant mesenchymal cell population ...
In a groundbreaking advancement for cancer research and personalized medicine, scientists in China have successfully established an extensive library of ...
