Tag: Parkinson’s disease

A new review in the Journal of Translational Medicine charts how magnetic resonance spectroscopic imaging is evolving from static metabolite ...

Nine European Parkinson's specialists have issued consensus recommendations for using the newly approved dual-release levodopa formulation IPX203 in patients with ...

Critical Path Institute and the University of Arizona have launched a two-year collaboration using human stem cell-derived neurons and new ...

A Bayesian network meta-analysis of 173 randomized trials finds mind–body exercise shows the largest effect on clinician-rated motor symptoms in ...

A new PLOS Biology essay proposes that a neuron's capacity to maintain its subtype-defining gene-regulatory machinery may set the stress ...

A prospective study of 85 Parkinson's patients found that a four-week multidisciplinary inpatient rehabilitation program produced large, sustained improvements in ...

A spatial multi-omics study in Nature Communications identifies disease-associated oligodendrocytes whose interleukin 33–ST2 signaling influences alpha-synuclein burden and motor symptoms ...

A new study shows that ten sessions of high-frequency magnetic stimulation targeting the primary motor cortex improved freezing of gait ...

A new resting-state fMRI study shows that Parkinson's disease-related brain network patterns can be detected in genetically at-risk people before ...

A two-stage study of 340 participants in Singapore has identified twelve autoantibodies elevated in Parkinson's disease patients, linked to translation ...

A 7 Tesla MRI study of early Parkinson's disease patients links anxiety to reduced caudate volume and distinct shape deformations ...

A multicenter Chinese study of 3,148 Parkinson's disease patients developed and validated interpretable survival prediction models and deployed the best-performing ...

A matched-cohort study finds that Parkinson's patients with nocturnal hypokinesia show slower turning, poorer backward walking, and fewer daily steps, ...

A multi-omics study of 67 Parkinson's disease patients and 64 controls reveals microbial-driven lipid and amino acid pathways, with gut-derived ...

Researchers have developed a chronic intranasal rotenone mouse model that reproduces the brain-first, olfactory-to-midbrain spread of alpha-synuclein pathology characteristic of ...

A new preclinical study shows that trigonelline, a coffee-derived alkaloid, reduces alpha-synuclein pathology and neuroinflammation in Parkinson's model mice while ...

A two-stage epigenome-wide meta-analysis of more than 2,000 individuals has identified thousands of DNA methylation sites where Parkinson's disease affects ...

Researchers converted spinach leaf extract into nitrogen-rich reduced graphene oxide that detects dopamine in human serum with high sensitivity, backed ...

Researchers used a consumer tablet app to capture facial blendshape features that objectively quantify Parkinson's hypomimia, revealing asymmetry and interaction ...

A new time-to-event analysis of early Parkinson's disease trials shows that large, clinically meaningful worsening thresholds can be detected within ...