Tag: Parkinson’s disease

A new MRI study finds that impaired glymphatic clearance, measured by the ALPS index, independently predicts the severity of drooling ...

Researchers used a vector-free CRISPR activation system to boost dopamine biosynthesis genes in cellular models of Parkinsonian neurotoxicity, finding modest ...

A new perspective in npj Parkinson's Disease proposes a six-dimensional MRI-based framework for capturing the biological heterogeneity of Parkinson's disease ...

University of Nottingham researchers found that shielding fruit flies from Earth's magnetic field altered mitochondrial function, lifespan and physical performance, ...

New research shows that environmental neurotoxicants damage mitochondria in ways that break down the nuclear pore complex and disrupt nucleocytoplasmic ...

Researchers behind a deep brain stimulation prediction algorithm respond to an external validation study, defending their methods and laying out ...

University of Bath chemists have mapped how tiny structural changes tune the colour and brightness of azulene-based fluorescent probes, producing ...

For decades, scientists have treated Alzheimer's and Parkinson's disease as problems of the brain alone. A new review published in ...

Indian researchers have synthesized arylidene indanone derivatives that restore motor function in Parkinson's model mice and memory in Alzheimer's model ...

Researchers at Kocaeli University combined RGB video features and skeleton-based motion features in a multimodal deep learning framework that detects ...

A new review in Biogerontology argues that the Hippo–YAP/TAZ signalling pathway acts as a central hub linking brain ageing, neurodegeneration, ...

A multi-omics study identifies the mitochondrial pyruvate carrier gene MPC2 as a causal link between hypoxia, mitochondrial energy failure, and ...

New research shows that the age-related decline of the mitochondrial protein CHCHD2 disrupts the mitochondria-lysosome axis and drives proteostatic collapse ...

Rutgers engineers have built a self-powered smart shoe that harvests energy from each footstep and uses onboard artificial intelligence to ...

A new review proposes the Iron-Brain Nexus framework to explain why the brain is uniquely vulnerable to iron-dependent ferroptotic cell ...

Researchers in New Delhi have developed a disposable paper-based electrochemical sensor that simultaneously detects Alzheimer's and Parkinson's disease biomarkers with ...

A multimodal imaging and voice-analysis study of early Parkinson's disease reveals that speech impairment arises from dopaminergic loss and striatal ...

For the first time, researchers have sequenced mitochondrial DNA from individual vulnerable brainstem neurons in Parkinson's disease, revealing extensive deletions ...

University of Oxford researchers have discovered that a specialised population of human microglia protects dopamine neurons in Parkinson's disease by ...

A mixed-methods analysis of 1,187 Parkinson's and dementia apps finds that only about two percent claim medical device certification, while ...