Plant Flavonoids Emerge as Multi-Target Weapon Against Drug-Resistant Tuberculosis
A new review maps how plant-derived flavonoids attack tuberculosis through multiple molecular mechanisms while outlining the structural features and delivery ...
Tag: oxidative stress
Nanoparticle Citrus Flavonoid Shields Kidneys in Mice with Cancer, Study Finds
A new study in Medical Oncology reports that diosmin loaded into chitosan nanoparticles reduced tumor burden and protected the kidneys ...
Diabetes May Silence the Nervous System’s Built-In Brake on Inflammation
A new review proposes that diabetic autonomic neuropathy disables the vagal inflammatory reflex, creating a self-reinforcing cycle of inflammation and ...
Dental Pulp Stem Cell Secretome Shows Promise for Stroke Recovery in Mice
A Chonnam National University study found that the human dental pulp stem cell secretome reduced oxidative stress and neuroinflammation while ...
Malic Acid and Moringa Leaf Extract Help Spinach Tackle Toxic Metal Stress
A new study finds that combining malic acid in the root zone with foliar Moringa leaf extract restores growth and ...
Betel Nut Chemical Shields Oral Cancer Cells From Copper-Driven Cell Death
New research shows that arecoline, the main alkaloid in betel nut, activates a ROS-NRF2-MT2A signaling axis that protects oral squamous ...
Liver and Brain Drive Separate Symptoms in Rare Inherited Epilepsy, Mouse Study Finds
A Johns Hopkins mouse study shows that liver dysfunction drives seizures while astrocyte defects in the brain drive psychiatric symptoms ...
Heatstroke Depletes a Heart-Protective Lipid, and Restoring It Saves Mice
A new mouse study shows that heatstroke depletes the anti-inflammatory lipid Maresin1 and that restoring it through the cardiomyocyte receptor ...
Turmeric Compound and Black Pepper Molecule Team Up to Block Liver Cancer in Rats
A new rat study in BMC Cancer reports that curcumin and piperine, especially in combination, prevent chemically induced hepatocellular carcinoma ...
Pennyroyal Oil Disrupts Hormones and Damages Liver and Fertility in Rats
A combined computational and rat study shows that pulegone-rich pennyroyal essential oil damages the liver and disrupts fertility through endocrine ...
Fire Extinguisher Plant Yields Essential Oil With Antioxidant and Antidiabetic Potential
The first GC-MS analysis of the essential oil from Pentanisia prunelloides leaves reveals a sesquiterpene-rich mixture with moderate antioxidant and ...
Clamworm Compounds Show Promise Against Alcoholic Liver Damage in Mice
Maillard reaction products derived from the marine clamworm Perinereis aibuhitensis protected mice against alcohol-induced liver injury by restoring antioxidant, anti-inflammatory, ...
Sheep Skin Genes Reveal Hidden Biology Behind Black and White Coats
RNA sequencing of black and white Hortobágyi Racka sheep reveals that coat color differences extend beyond pigment genes into ion ...
Roasted or Raw, Argan Oil Shields Diabetic Hearts and Livers in Rat Study
A new rat study shows that both roasted and unroasted argan oil protect diabetic rats against heart and liver damage, ...
Pomegranate Peel Powder Boosts Immunity and Fertility in Goldfish, Study Finds
A preliminary feeding trial found that goldfish fed diets supplemented with 4 percent pomegranate peel powder showed significantly enhanced systemic ...
Triaptosis: Scientists Unveil a New Form of Cell Death Centered on Endosomes
A new review in Cell Death & Discovery proposes triaptosis, an endosome-centered form of ROS-regulated cell death driven by oxidative ...
Kidney Disease in Newborn Mice Drives Iron Buildup in the Developing Brain
A new mouse study shows that severe kidney disease in newborns causes iron to accumulate throughout the developing brain, offering ...
Antioxidant Protein Thioredoxin-1 Reshapes Oligodendrocyte Lineage Cells in Parkinson’s Model
A new study shows that the antioxidant protein thioredoxin-1 regulates the expansion of oligodendrocyte lineage cells and the accumulation of ...
Anti-Inflammatory, Antioxidant-Rich Diets Linked to Longer Survival in Fatty Liver Disease
A large NHANES-based study finds that pro-inflammatory diets roughly double mortality risk in fatty liver disease while antioxidant-rich diets are ...
Old Antipsychotic Meets Mitochondrial Blocker in Two-Drug Strike on Cancer Cells
New research shows that pairing the decades-old antipsychotic chlorpromazine with the mitochondrial fission inhibitor mdivi-1 sharply boosts cancer cell death ...
