Blood DNA biomarkers track progression during prostate cancer radioligand therapy
A prospective observational study linked circulating tumor DNA fraction and copy-number burden with progression and survival in 78 patients receiving ...
Tag: overall survival
Subdivision of metachronous metastatic nasopharyngeal carcinoma based on the framework of TNM-9: A recursive partitioning analysis of real-world data
A real-world analysis of 218 patients with metachronous metastatic nasopharyngeal carcinoma proposed a prognostic classification combining metastatic-lesion count with disease-free ...
Acute pancreatitis linked to poorer survival in checkpoint inhibitor cohort
A retrospective single-center cohort found that acute pancreatitis during immune checkpoint inhibitor therapy was associated with treatment disruption and substantially ...
Retrospective analysis finds uncertain HER2-low survival link in esophagogastric junction adenocarcinoma
A retrospective study of 74 resected esophagogastric junction adenocarcinomas found longer overall survival in HER2-low tumors, but HER2-low status was ...
Half-matched transplants show high survival in severe aplastic anemia
A Johns Hopkins retrospective cohort study found 96% overall survival among 23 children and young adults with severe aplastic anemia ...
Retrospective study links combined HAIC and systemic therapy to outcomes in advanced liver cancer
A retrospective cohort of 331 initially diagnosed patients with HCC and Vp3/4 portal vein tumor thrombosis found a 61.3% objective ...
Immune Gene Variant HLA-C*04 Linked to Poorer Survival After Liver Cancer Surgery in Hawaii
A retrospective Hawaiian study of 84 surgically treated hepatocellular carcinoma patients found that carrying at least one copy of the ...
Endothelial p16 expression marks a favorable-prognosis subgroup of clear cell renal cell carcinoma
A tissue microarray study of 347 clear cell renal cell carcinomas finds that p16 expression in intratumoral blood vessels, rather ...
Surgery and radiotherapy linked to longer survival in grade 4 brain tumors
A retrospective study of 102 adults with grade 4 gliomas in the Democratic Republic of the Congo linked gross total ...
Antibody-Drug Conjugate Cuts Death Risk by 54% in Relapsed Small-Cell Lung Cancer
The phase III TAISHAN-302 trial found that the anti-B7-H3 antibody-drug conjugate Tam-Peli reduced the risk of death by 54 percent ...
Checkpoint inhibitors improve survival in pMMR metastatic colorectal cancer meta-analysis
A meta-analysis of six randomized trials found that adding PD-1/PD-L1 inhibitors to chemotherapy was associated with longer progression-free and overall ...
Ivonescimab Extends Overall Survival Over Pembrolizumab in PD-L1-Positive Advanced Lung Cancer
A prespecified interim analysis of the phase 3 HARMONi-2 trial shows ivonescimab achieved median overall survival of 30.8 months versus ...
Retrospective single-center Rwanda cohort reports treatment gaps and survival estimates
A retrospective cohort of 163 patients treated at one Rwandan cancer center reported estimated median overall survival of 3.68 years ...
Prognostic significance of systemic inflammatory and peripheral immune profiles in differentiated thyroid carcinoma: a retrospective cohort study
A retrospective study of 430 surgically treated patients links elevated inflammation, thyroid-related blood markers and selected immune-cell measures with survival ...
Prognostic significance of folate receptor alpha expression in endometrial serous carcinoma: implications for patient stratification and targeted therapy
A retrospective study of 47 patients found that high folate receptor alpha expression was independently associated with shorter progression-free survival ...
Transformer AI Model Predicts Survival in Rare Lung Neuroendocrine Cancers
A two-center retrospective cohort study of 823 surgically resected pulmonary neuroendocrine carcinoma patients found that a Transformer-based AI model achieved ...
Checkpoint inhibitors linked to longer unadjusted progression-free survival in advanced thoracic tumors
A single-center cohort study linked checkpoint inhibitor-containing therapy with longer unadjusted progression-free survival in advanced SMARCA4-deficient thoracic tumors, but adjusted ...
Combining Liver Artery Therapies With Immunotherapy Shows Survival Gains in Advanced Liver Cancer Review
A meta-analysis of fourteen retrospective cohort studies associates TACE-HAIC combined with targeted therapy and immune checkpoint inhibitors with improved survival ...
Lymph Node Status After Chemoimmunotherapy Predicts Survival in Esophageal Cancer
A retrospective cohort study of 194 patients with esophageal squamous cell carcinoma found that postoperative pathological lymph node stage, rather ...
Durvalumab and olaparib combination extends survival in advanced endometrial cancer
Updated Phase 3 DUO-E trial results presented at ESMO 2026 show that durvalumab plus olaparib after chemotherapy achieved a median ...
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