Tag: organoids

Hundreds of patient-derived cancer models expanded dependency mapping and revealed vulnerabilities linked to mutations, cellular states and treatment history, while ...

A mouse organoid system shows that defined signals can separately initiate acinar-to-ductal conversion, sustain metaplastic expansion and promote partial redifferentiation ...

Researchers at Kumamoto University report that high salt tonicity, acting through the transcription factor NFAT5, drives the morphological, transcriptional, and ...

A new review maps how patient-derived induced pluripotent stem cells and three-dimensional vascular and neurovascular organoids are transforming Moyamoya disease ...

Patient-derived microtumors grown from core needle biopsies as small as a few cubic millimeters of tissue successfully predicted breast cancer ...

The UC Davis NAMs Testing Center offers an independent, fit-for-purpose evaluation model for organoids, microphysiological systems and computational tools as ...

A single letter change in a protein that shepherds RNA through the splicing machinery may be enough to rewire thousands ...

A new review details how tissue engineering, 3D bioprinting, tissue chips, and biosensors are turning orbital microgravity into a powerful ...

Researchers at Tufts University and Boston University report that low-dose mixtures of common bisphenols can disrupt normal breast development in ...

A new study from the Stowers Institute for Medical Research shows that cell division actively reshapes epithelial tissue, with dividing ...

MIT engineers have created a handheld microfluidic device that gently collects living cells from targeted tissue locations, potentially enabling earlier ...

Scientists have grown the first organoids of the visceral pleura, the thin membrane that envelops the lungs, and shown that ...

Roche researchers validate a human 3D immune-containing colorectal cancer assembloid platform that captures interferon-gamma signaling, uncovers fibroblast plasticity, and demonstrates ...

The International Society for Stem Cell Research has opened registration and abstract submissions for its 25th anniversary Annual Meeting, to ...

WEHI researchers have discovered that gamma delta T cells can recognise and kill small cell lung cancer, and that two ...

A high-resolution spatial transcriptomic atlas of human ovarian and peritoneal endometriosis lesions reveals conserved fibroblast niches and sensory neuroimmune interactions ...

A single-cell multi-omic atlas of neuroendocrine carcinoma of the cervix identifies DLL3 as a driver of immune evasion and validates ...

Angiogenesis research is transforming cancer, eye disease, and regenerative medicine, and its leading journal's new impact factor underscores the field's ...

A Johns Hopkins study shows chronic cigarette smoke exposure reprograms distinct lung stem cell populations through epigenetic changes, determining whether ...

Researchers have built vascularized, immune-integrated human skin assembloids from stem-cell-derived organoids that model atopic dermatitis-like inflammation and respond to approved ...