Tag: next-generation sequencing

A study of 58 patients found that ovarian cancer ascites-derived cell blocks supported immunohistochemical diagnosis and detected homologous recombination repair ...

A 2026 single-patient case report identifies a previously unreported p.Y76C variant in ELOC (TCEB1)-mutant renal cell carcinoma in a 52-year-old ...

A retrospective study of 73 Chinese patients links micropapillary/solid and lepidic components in invasive non-mucinous lung adenocarcinoma with distinct clinical, ...

A new Oncotarget case report details how the WIN Consortium's international molecular tumor board evaluated investigational EGFR, MDM2, CDK4/6 and ...

A 46-year-old woman's uterine tumor resisted classification until two surgeries, immunohistochemistry, and next-generation sequencing excluded Ewing's sarcoma and revealed an ...

A case report describes a family carrying an inherited STAT5B variant of uncertain significance in which anemia developed only in ...

A quantification study of 130 archived FFPE tissue blocks from Strasbourg and Geneva shows that many century-old specimens still contain ...

A retrospective single-center analysis of 452 Chinese patients with non-small cell lung cancer associated compound and co-occurring EGFR mutations with ...

A retrospective study of 606 clinically referred people in northeastern Mexico characterized two-field HLA allele and haplotype diversity, but its ...

A comparative genomic study produced the first mitochondrial genomes for two Atacama Region land snails and strongly supported their relationships ...

A targeted-sequencing case-control study of 50 people found that one CCR2 variant was more frequent in the sarcoidosis group, suggesting ...

A 1,500-patient next-generation sequencing study from Gazi University reveals EGFR and KRAS as dominant drivers in advanced NSCLC, with distinct ...

A clonal DNA barcoding platform pools organoids from many colorectal cancer patients in one dish, tracking drug sensitivity through barcode ...

A comprehensive genetic and clinicopathological analysis of 18 patients with mosaic RASopathies reveals that postzygotic mutations in HRAS, KRAS, BRAF, ...

A sweeping narrative review charts how molecular genetics turned non-malignant blood disorders into the proving ground for modern diagnostics and ...

A Hungarian study of 45 pediatric rhabdomyosarcoma cases found TRK protein expression in 38 percent of tumors—concentrated in the aggressive ...

A single next-generation sequencing panel covering 116 cancer-related genes matches the traditional multi-platform approach for classifying endometrial carcinoma, while catching ...

A new study shows that sequencing tumor DNA in ascites, pleural fluid, cerebrospinal fluid, and pericardial effusions can detect malignancies ...

A Chinese-developed sequencing assay measuring donor-derived cell-free DNA identified a 0.33% threshold for detecting acute rejection in heart transplant recipients, ...

A comprehensive review shows circulating tumour DNA offers powerful prognostic insight across all major mCRPC treatments, but its predictive use ...