Gut microbes may hold the key to Alzheimer’s and Parkinson’s disease
For decades, scientists have treated Alzheimer's and Parkinson's disease as problems of the brain alone. A new review published in ...
Tag: neurodegenerative disease
Brain Chemistry Meets Immune Fire: How Neurotransmitters Steer the NLRP3 Inflammasome
A new narrative review maps the complex, context-dependent crosstalk between neurotransmitter systems and the NLRP3 inflammasome, revealing bidirectional regulation with ...
Intranasal Herpes Virus Remodels Brain Immune Cells in a Region-Specific Pattern
A multiomic study in PLOS Pathogens shows that intranasal HSV-1 infection drives localized, interferon-dominated remodeling of microglia in discrete brainstem ...
Lightweight AI Tool Outsmarts Deep Learning at Spotting Disordered Proteins
A researcher at IIIT Allahabad has developed IDP-T5CKNN, a lightweight protein language model method that outperforms more than 20 existing ...
Molecular Brake Found That Keeps Lipid-Scrambling Protein TMEM63B Switched Off
Researchers at Institute of Science Tokyo show that the C-terminal tail of TMEM63B, particularly the Leu776 residue, acts as an ...
AI Meets Living Cells in $28.6 Million Bid to Predict Protein Misfolding Before Disease Strikes
A Stowers Institute scientist will help lead a $28.6 million ARPA-H effort to generate billions of protein aggregation measurements and ...
Blood Cells From 80-Year-Olds Rejuvenated Into Brain Cells With Molecular Age Under 20
University of Bonn researchers directly reprogrammed red blood cell precursors from elderly donors into neural stem cells whose epigenetic clocks ...
Multimodal AI in Mental Health Care Leans Heavily on a Single Dataset, Review Finds
A scoping review of 19 studies finds that multimodal AI fusing raw images with non-image data in mental and cognitive ...
Enzyme-Digested Edible Bird’s Nest Boosts Nerve Growth Factor Signaling in Lab-Grown Neurons
New research shows that enzyme-digested edible bird's nest amplifies nerve growth factor signaling through the TrkA-ERK1/2-CREB-BDNF pathway, priming PC12 cells ...
New AI Reads Brain Scans Four Ways to Spot Alzheimer’s Stages and Know When It Is Unsure
A new multi-stream deep learning framework called MS-AtroNet combines convolutional, state-space, wavelet, and evidential components to classify Alzheimer's MRI slices ...
Gene Therapy Slows ALS Onset in Mice Models
In a groundbreaking study, researchers have unveiled a potential breakthrough in the treatment of Amyotrophic Lateral Sclerosis (ALS) through innovative ...
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