A prospective cohort study in Delhi found high phenotypic and spoligotype concordance between drug-resistant tuberculosis patients and culture-positive household contacts, ...
A systematic review reveals how host and mycobacterial non-coding RNAs regulate immune signaling, bacterial adaptation, and diagnostic biomarker discovery in ...
A prospective evaluation demonstrates that a CRISPR-Cas13a assay targeting cell-free bacterial DNA in pleural effusion supernatant achieves 80.5 percent diagnostic ...
A curated collection of studies reveals how diverse intracellular pathogens manipulate host autophagy and outlines strategies for developing host-directed therapies ...
A retrospective case series of five patients reveals that acute pulmonary embolism can complicate tracheobronchial tuberculosis, presenting primarily with unexplained ...
A study of 408 household contacts of hospitalized pulmonary tuberculosis patients found a 32.84 percent QuantiFERON-TB Gold Plus positivity rate ...
A prospective study of 197 adults with suspected central nervous system infection found that cerebrospinal fluid metagenomic sequencing identified reportable ...
A systematic review in Cameroon found a 4.9 percent pooled prevalence of multidrug-resistant tuberculosis, with significantly elevated rates among previously ...
A cross-sectional study of 836 Mycobacterium tuberculosis clinical isolates at a Thai referral hospital revealed a 5.2% discordance rate between ...
A cross-sectional survey in Blantyre, Malawi found that tuberculosis immunoreactivity diverged sharply between young men and women in their twenties ...
A proof-of-concept targeted Nanopore sequencing assay demonstrated high accuracy for detecting drug-resistant tuberculosis mutations in culture, but variable coverage limited ...
A new study reveals that the lipid mediator Resolvin D5 reprograms macrophage metabolism via GPR32 signaling, impairing the immune system's ...
A study reveals that type I interferon-induced viperin enables Mycobacterium tuberculosis survival in macrophages by suppressing the protective COX-2, PGE2, ...
A prospective multicenter study across ten clinical centers in China determined that baseline delamanid resistance emerged in only 0.76 percent ...
A new review argues that the predominant clonal evolution model, in which bacterial lineages stay genetically stable across space and ...
A computational study identified five natural compounds with strong predicted binding to the Rv1509-encoded DNA methyltransferase of Mycobacterium tuberculosis, supported ...
A study of 335 Mycobacterium tuberculosis isolates in China found a pretomanid 99th percentile MIC of 0.25 mg/L in 7H9 ...
A retrospective study of 425 patients in China found metagenomic next-generation sequencing detected tuberculosis with 90.1% sensitivity, outperforming six routine ...
A computational study has designed a multi-epitope tuberculosis vaccine candidate from conserved immunoreactive peptides, fused to a non-toxic enterotoxin fragment ...
A new study reports that the kinase CK2α regulates P-glycoprotein expression in macrophages through two signaling pathways, and that combining ...
