Bamboo-Shoot Probiotic Shields Gut and Tames Inflammation in Mice
The strain, Lentilactobacillus hilgardii DSB22, was isolated from fermented shoots of Bambusa merrilliana, locally known as "bayug," a bamboo species ...
Tag: Mucosal immunity
Antibodies That Coat a ‘Good’ Vaginal Bacterium May Help Guard Against Preterm Birth
New research shows that IgG antibodies coating the beneficial vaginal bacterium Lactobacillus crispatus are linked to lower inflammation and a ...
CAR-T Cells Linger in the Gut and Drive Severe Intestinal Inflammation, Mount Sinai Study Finds
Chimeric antigen receptor T cell therapy has redefined the treatment of multiple myeloma, offering deep and durable remissions to patients ...
Nose and Blood Tell Different Recovery Stories in Allergy Immunotherapy Study
Paired metabolomic profiling of nasal secretions and plasma reveals that allergic rhinitis and its recovery during subcutaneous immunotherapy unfold through ...
Fish Guts Reveal Ancient Origins of Antibody Factory Structures
Researchers have discovered inducible germinal center-like structures in the gut of common carp, showing that sophisticated mucosal antibody responses evolved ...
Gum Inflammation May Quietly Weaken the Bladder and Vagina After Menopause
A new narrative review proposes that periodontal inflammation may amplify genitourinary vulnerability during and after menopause through systemic inflammatory signals ...
Breast milk-derived antibody preparation shields mice from influenza infection
A polyclonal secretory IgA preparation purified from pooled donor breast milk neutralized multiple respiratory viruses in vitro and reduced illness ...
Gut Barriers and Maternal Antibodies Explain Patchy Rotavirus Vaccine Success
A new review explains why oral rotavirus vaccines protect children far less effectively in low- and middle-income countries, citing maternal ...
Fish Antibody Transport Reveals an Ancient Secret of Mucosal Immunity
Structural analysis of teleost fish shows that pIgR binds tetrameric IgM directly without the joining chain in an unconventional 2:1 ...
How Pseudomonas aeruginosa Hijacks Protective T Cells to Fuel Cystic Fibrosis Lung Damage
New research shows Pseudomonas aeruginosa reprograms protective Th17 cells into pathogenic interferon-gamma-producing effectors that directly damage the cystic fibrosis lung ...
Antibodies, Not Just Abundance: IgA Surveillance Emerges as a Hidden Architect of the Gut Microbiome
A new quantitative framework reveals that IgA antibody targeting organizes the gut microbiome and fragments detectably in early multiple sclerosis.
Oysters Use a Chemical Redox Switch in Mucus to Control Their Microbiome
New research shows that Pacific oysters regulate a mucus defensin's antimicrobial power through extracellular redox chemistry, revealing a chemical switch ...
Gut diseases in miniature: organoids and organ-on-a-chip models reshape gastrointestinal research
A Nature Biomedical Engineering review synthesises how organoids and organ-on-a-chip technologies are transforming the modelling of inflammatory, infectious and neoplastic ...
New Research Reveals Mucus Molecules That Inhibit Salmonella Infection
In a groundbreaking study emerging from the Massachusetts Institute of Technology, researchers have uncovered a crucial mechanism by which the ...
Edible Cholera vaccine made of powdered rice proves safe in phase 1 human trials
Study points towards role of gut microbiome in vaccine effectiveness A new vaccine to protect against deadly cholera has been ...
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