Tag: molecular imaging

A Swedish clinical trial reveals that positron emission tomography with the PARP1-selective radiopharmaceutical AZ14193391 is feasible, safe, and delivers a ...

A preliminary prospective study shows that 3.0 T glucoCEST MRI is feasible for detecting bladder cancer and distinguishing tumors from ...

Researchers demonstrated that TSPO-targeted PET imaging with DPA-714 selectively maps early inflammatory muscle remodeling downstream of peripheral nerve crush in ...

A histological pilot study demonstrates that PET uptake of the radiotracer SiTATE correlates strongly and significantly with somatostatin receptor subtype ...

A histopathology-validated study demonstrates that FET PET detects non-contrast-enhancing glioblastoma with substantially higher sensitivity than contrast-enhanced MRI across tissue samples ...

Researchers developed an automated zinc-mediated radiosynthesis of fluorine-18 fluoroflutamide but observed limited androgen receptor engagement and unexpected mass effects in ...

Researchers engineered a dimeric radioligand targeting fibroblast activation protein that demonstrated superior tumor accumulation and extended retention over a clinical ...

In a prospective single-arm trial of 42 patients after nephrectomy, 68Ga-NY104 PET/CT detected suspected metastatic or recurrent clear cell renal ...

Two case reports in EJNMMI Reports identify false-positive Ga-FAPI PET/CT uptake in hepatocellular carcinoma patients following stereotactic body radiation therapy, ...

A prospective study demonstrates that edited magnetic resonance spectroscopy can measure critical antioxidant metabolites noninvasively in patients with isocitrate dehydrogenase-wildtype ...

A pharmacokinetic modeling study shows that blood-brain barrier permeability, rather than target binding rate, is the primary driver of dynamic ...

Ahead-of-print studies in The Journal of Nuclear Medicine report advances in targeted radiotheranostics, molecular imaging of kidney fibrosis, and clinical ...

A scoping review of Turkish literature indicates that FAP-targeted PET/CT functions as a selective, question-driven imaging tool rather than a ...

A preclinical evaluation of the radiolabelled Hsp90 inhibitor onalespib demonstrated tumour binding but revealed rapid metabolism and negligible brain penetration.

Preclinical molecular imaging targeting active matrix metalloproteinases revealed that aging elevates vascular remodeling signals and predicts rupture-related survival in murine ...

A pilot study evaluating integrated PET and MRI revealed that molecular tracer uptake strongly correlates with cellular density and immunohistochemical ...

A joint Monte Carlo reconstruction algorithm utilizing both lutetium-177 photopeaks reduces scan-to-scan variability by up to 3.2-fold compared to conventional ...

A dynamic total-body PET/CT study of Ga-HER2 Affibody in HER2-positive breast cancer patients measured organ biodistribution, an effective dose of ...

A new review consolidates the synthetic strategies used to convert macrocyclic chelators such as DOTA and NOTA into bifunctional agents ...

A prospective imaging study of eleven patients with five different cancers found that I-PARPi SPECT/CT uptake corresponded with PARP immunohistochemistry ...