Tag: microglia

A new narrative review maps how vitamin D deficiency may sit at the mechanistic crossroads of neuropathic pain and cognitive ...

In BV2 microglial cells, esketamine suppressed lipopolysaccharide-induced M1 polarization by selectively acting on the NMDAR2A receptor subtype and activating mTOR ...

A new nanomaterial called TPTN reduces uveitis inflammation by suppressing microglial activation and inhibiting the JAK2-STAT1 signaling pathway in mouse ...

A new review argues that inflammatory signaling between microglia and astrocytes may help initiate and maintain the central sensitization underlying ...

A matched PET and post-mortem study links elevated TSPO binding in frontotemporal dementia primarily to a greater burden of CD68-positive ...

A 2026 mini review concludes that microglial metabolic states may connect brain pathology with adult neurogenic niche remodeling through phagocytosis, ...

StrokeTime integrates 414,359 single-cell transcriptomes from mouse ischemic-stroke studies to trace immune, vascular, glial and neuronal changes from hyperacute injury ...

A mouse study found that inherited mitochondrial DNA variation was associated with age-dependent retinal respiratory-chain remodeling, mitochondrial DNA damage and ...

A new study shows the natural chalcone cardamonin calms LPS-activated microglia by suppressing the EGFR/PI3K/AKT1/ERK/NF-kappaB signaling axis, indirectly protecting SH-SY5Y ...

A new review proposes that age-related remodeling of the sugar layer lining brain blood vessels could converge with galectin-3 inflammatory ...

A new Frontiers in Pharmacology perspective argues that dysregulated glucocorticoid receptor signaling is a shared upstream driver of chronic inflammation ...

A human stem-cell model recreates early yolk sac immune development and shows that a single progenitor population can generate specialized ...

A new review maps how traditional Chinese medicine compounds, herbal formulas, and electroacupuncture modulate the cGAS-STING neuroimmune pathway, revealing that ...

Age-related hearing loss, or presbycusis, has long been viewed as an inevitable consequence of wear and tear on the delicate ...

A new review in Frontiers in Neurology examines how low-intensity red to near-infrared light may modulate the neuroinflammatory processes shared ...

A carefully dosed treadmill rehabilitation protocol shifted the inflammatory environment after spinal cord injury toward repair, preserving nerve fibres, muscle ...

A Bangladeshi case-control study finds that patients with generalized anxiety disorder show significantly reduced interleukin-4 and elevated MCP-3 blood levels ...

A new review in Results in Chemistry details how programmable DNA nanobiosensors combined with artificial intelligence could enable early detection ...

New research shows the BTK inhibitor ibrutinib accelerates remyelination by reprogramming microglial extracellular vesicles to carry the repair-promoting microRNA miR-223.

A new perspective argues that pairing non-invasive brain stimulation with pro-remyelinating drugs could target both oligodendrocyte differentiation and the hostile ...