New SEM Protocol Maps Wear Debris Inside Joint Tissue
Published in Applied Microscopy, the study presents a general protocol designed to characterize micro- and nano-structural features of debris while ...
Tag: methodology
New analysis suggests tDCS motor learning results depend on individual biology
A new commentary argues that null findings in tDCS motor learning studies may result from ignoring biological sex and individual ...
Protocol outlines review of MLTC prediction models
A new protocol for a systematic review aims to compare methodological approaches for developing clinical prediction models for individuals with ...
New metric weighs prediction models across every clinical decision threshold
Researchers have introduced a continuous net benefit metric that summarises the clinical utility of prediction models across a whole range ...
Team-Based Rapid Qualitative Analysis Gets a Detailed How-To for Health Researchers
A new methodological paper details a five-phase, in-person team-based rapid qualitative analysis approach refined across four Ontario health research projects.
Early-Care Variables May Distort the Apparent Benefit of Neurosurgery-Capable Hospitals
A letter in Neurocritical Care argues that an odds ratio of 0.51 for traumatic brain injury mortality may reflect adjustment ...
New lung ultrasound consensus arrives 14 years late, and critics say it falls short
A new editorial in Intensive Care Medicine argues that the long-awaited update to the 2012 lung ultrasound consensus omits certainty-of-evidence ...
Researchers Defend Network Meta-Analysis Comparing Hereditary Angioedema Drugs
The authors of a contested network meta-analysis rebut claims that lanadelumab and garadacimab perform similarly in hereditary angioedema, defending their ...
Grip strength alone may miss key signs of successful aging, commentary argues
A new commentary argues that grip strength may not fully capture functional determinants of successful aging and flags methodological concerns ...
Heavy Alcohol and Aneurysm Rupture: Letter Flags Key Gaps in Meta-Analysis
A letter to the editor outlines methodological concerns about a meta-analysis linking heavy alcohol consumption to intracranial aneurysm rupture.
New Bayesian Method Maps How Green Transport Policies Deliver Hidden Health Benefits
A new four-step methodology combining Theories-of-Change, Bayesian credence assessment and causal diagrams predicts health co-benefits of sufficiency policies, finding that ...
Nitrate Health Risk Assessments Riddled with Methodological Errors, Study Warns
A discussion paper in Environmental Geochemistry and Health identifies recurring methodological errors, including misapplied reference doses and unit inconsistencies, that ...
Scientists Challenge HERV-K102 Findings in Acute Myeloid Leukemia Study
A correspondence in Blood Research raises four methodological concerns about a study linking HERV-K102 envelope deletion to pyroptosis in acute ...
Researchers Challenge Claim That C1 Inhibitor Beats Sebetralstat in Hereditary Angioedema
A new letter to the editor argues that a widely reported indirect comparison overstating recombinant C1 inhibitor's advantage over sebetralstat ...
How to build clinical prediction models that survive new populations: a scoping review maps the methods
A scoping review of 18 studies categorises the emerging methods for building clinical prediction models that keep their performance in ...
Lean Methodology Cuts Surgical Waste in the Preoperative Phase, Review Finds
A scoping review of 27 studies shows Lean methodology reduces redundant testing, scheduling delays, and communication gaps in the preoperative ...
Ensemble voting method tackles the problem of imperfect clinical reference standards in physiological monitoring
When a new monitoring device disagrees with the clinical assessment it is supposed to improve, standard diagnostic accuracy analyses cannot ...
Deep Learning’s Anomaly Detection Supremacy May Be an Illusion, Study Finds
A reproducibility study of 18 influential papers finds that data leakage, silently modified datasets, and underspecified baselines have inflated claims ...
New Guidance Aims to Sharpen Early-Warning Signals in Epidemic Surveillance
A new PLOS Digital Health review sets out methodological recommendations for making leading indicator analyses in epidemic surveillance reliable and ...
Hidden patient groups revealed: when a popular statistics tool helps and when it misleads
A new commentary in Supportive Care in Cancer urges researchers to distinguish between mono-construct and multi-construct uses of latent profile ...
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