Bioinformatics Study Uncovers How Constricted PBP2a Active Site Drives MRSA Resistance
A comprehensive bioinformatics study reveals that severe active site constriction and low binding affinity in penicillin-binding protein 2a explain why ...
Tag: methicillin-resistant Staphylococcus aureus
Ouagadougou Staph Isolates Carry mecA and SCCmec Resistance Determinants
Researchers in Ouagadougou detected mecA resistance genes and SCCmec IVa cassettes among cefoxitin-resistant Staphylococcus aureus strains isolated from hospital clinical ...
Molecular Biophysics Uncovers New Vulnerabilities and Resistance Mechanisms Across Pathogenic Microbes
A newly compiled research collection uncovers the physical and molecular mechanisms governing drug resistance and virulence across bacterial and fungal ...
Sinus Tract Presence Associates With Documented Microbiological Positivity in Chronic Osteomyelitis
A retrospective cohort study in Northwest China found that sinus tract presence was independently associated with documented microbiological positivity in ...
Machine Learning Predicts Methicillin Resistance in Intensive Care Staphylococcus aureus Infections
Researchers developed an interpretable machine learning model using ICU data that achieved good discrimination in estimating methicillin resistance among patients ...
Enterococcus faecalis Linked to Higher MRSA Co-Colonization in Post-Acute Care
A study in three Great Lakes post-acute care centers found facility of stay influenced enterococcal species distribution, while Enterococcus faecalis ...
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