Tag: Meta-analysis

Direct-acting antiviral drugs have already rewritten the story of hepatitis C. What once required a year of interferon injections with ...

Urea-Boosted Moisturizers Emerge as Front-Runners for Dry Skin in Diabetes

A Cochrane-grade systematic review and meta-analysis of 12 randomized controlled trials finds that humectant-enriched moisturizers, especially urea-based creams, significantly outperform ...

Newer Anti-Nausea Drug Beats Ondansetron in Preventing Chemotherapy Vomiting, Review Finds

A new meta-analysis of eight randomised controlled trials finds that palonosetron significantly outperforms ondansetron in preventing vomiting during the acute, ...

When Expectant Fathers Quit: The Strongest Finding Yet in Pregnancy Smoking Cessation

A major systematic review finds father-directed smoking cessation programs are the most effective intervention in pregnancy, while socioeconomic support and ...

Roads Cut Wildlife Numbers by Nearly a Third, Landmark Meta-Analysis Finds

A meta-analysis of 643 effects from 160 studies finds road proximity is associated with roughly 32 percent lower wildlife outcomes, ...

Lower Lenvatinib Starting Doses Show No Clear Advantage in Advanced Endometrial Cancer

A new systematic review and meta-analysis finds that starting lenvatinib below 20 mg with pembrolizumab neither clearly preserves tumor response ...

Itch Relief Arrives Before Skin Healing in Prurigo Nodularis, Landmark Analysis of 11 Trials Finds

A new meta-analysis of 11 randomized trials shows dupilumab and nemolizumab deliver robust itch and lesion relief in prurigo nodularis, ...

Probiotic strain shortens childhood diarrhea by about 16 hours, but evidence remains shaky

An updated meta-analysis of six randomized controlled trials finds that Limosilactobacillus reuteri DSM 17938 modestly shortens diarrhea duration in children ...

PET/CT Radiomics Before Treatment Best Predicts Esophageal Cancer Therapy Response, Meta-Analysis Finds

A new systematic review and meta-analysis finds that pre-treatment PET/CT radiomics outperforms post-treatment imaging for predicting pathological complete response in ...

When Cancer Care Follows the Rulebook: Guideline Adherence Shapes Colorectal Cancer Survival

A new systematic review and meta-analysis finds that adherence to colorectal cancer clinical practice guidelines is linked to significant survival ...

CAR T-Cell Therapy Shows Durable Survival Gains in Aggressive Brain Lymphoma, Pooled Analysis Finds

A systematic review and meta-analysis of 23 studies and 547 patients finds that CD19-directed CAR T-cell therapy delivers encouraging one-year ...

New Trial Evidence Reshapes the Case for Left Atrial Appendage Occlusion in Atrial Fibrillation

A sweeping review of randomized trial evidence finds that left atrial appendage occlusion reduces non-procedural bleeding but does not lower ...

Vancomycin-Resistant Enterococcus Found in Nearly One in Five Blood Cancer Patients Worldwide

A global meta-analysis of 120 studies finds vancomycin-resistant enterococci in 18.4 percent of patients with haematological malignancies, with prevalence approaching ...

Sex Work and Male-With-Male Sex Sharply Raise HIV Risk for People Who Inject Drugs, Global Analysis Finds

A global meta-analysis finds that people who inject drugs who engage in sex work or male-with-male sex face substantially elevated ...

Nurses Really Can Cut Patients’ Drinking, Major Meta-Analysis of 16 Trials Finds

A new meta-analysis of sixteen randomized controlled trials finds that nurse-led interventions significantly reduce alcohol screening scores, consumption, and binge ...

High-Power Lasers Outshine Low-Level Therapy for Deep-Tissue Pain, Landmark Review Finds

A meta-analysis of 105 controlled trials finds that Class IV high-intensity laser therapy delivers large, durable pain relief and structural ...

Simple Blood Test Marker Signals Hidden Lymph Node Spread in Early Lung Cancer

A meta-analysis of thirty studies finds that elevated preoperative CEA is strongly associated with occult lymph node metastasis in clinical ...

One Brain Map, Two Diseases: Alzheimer’s and Multiple Sclerosis Share a Genetic Signature of Shrinkage

A large trans-disease meta-analysis of more than 6,900 brain scans finds that Alzheimer's disease and multiple sclerosis share a common ...

Belly-Pumping CPR Shows Promise for Restarting Hearts, but Evidence Stays Shaky

A new systematic review of eight randomized trials finds that active abdominal compression-decompression CPR speeds the return of spontaneous circulation ...

Infections May Strike One in Five Women With Gestational Diabetes, Global Analysis Finds