Tag: Medicinal Chemistry

The University of Bath has appointed Professor John Bower, formerly Regius Professor of Chemistry at Liverpool, as the new Raymond ...

A comprehensive review maps how strategic chemical modifications to the purine scaffold yield potent drug candidates against cancer, malaria, drug-resistant ...

Researchers at ETH Zurich and Roche have combined active learning with geometric and self-supervised deep learning to predict C–H borylation ...

Chemists have fused nitrofuran groups onto ciprofloxacin to create hybrid antibiotics up to sixteen times more potent than the original ...

Ohio State chemist David Nagib has been named a 2026 Blavatnik National Awards laureate for pioneering radical and carbene chemistry ...

Chemists at the Max-Planck-Institut für Kohlenforschung have developed a two-step, nickel-catalysed method that builds 3,3-diaryloxetanes, valuable ketone bioisosteres for drug ...

Chemists have developed a borane-activated radical strategy that opens unactivated N-alkyl aziridines regioselectively and funnels them into copper- and nickel-catalysed ...

Chemists have synthesized ten novel α-aminotetrazole compounds in a single-pot Ugi–azide reaction and identified an ortho-fluorinated lead with potent antibacterial ...

A Baylor College of Medicine-led team combined high-throughput proteomics and AI-based structural prediction to discover and optimize a new class ...

Northwestern University chemists have developed an electrochemical strategy that directly couples two fleeting carbon-centred radicals from abundant carboxylic acids and ...

A virtual library of 30 isoniazid-based Schiff base derivatives was computationally screened, and the top-ranked compound SLB-5 was synthesized and ...

Chemists have created a coumarin-based compound that inhibits tyrosinase twenty times more potently than kojic acid while also blocking the ...

A new review consolidates the 2025-2026 wave of pyrazole derivatives, revealing sub-micromolar anticancer leads, nanogel delivery gains, nanomolar enzyme inhibitors ...

In an intriguing advancement within the realm of medicinal chemistry, researchers have unveiled innovative methodologies involving palladium-catalyzed Suzuki–Miyaura and Buchwald–Hartwig ...

In the ever-evolving landscape of synthetic chemistry, triazolopyridines have emerged as a unique and versatile class of compounds. These compounds ...