Tag: mechanotransduction

A new hypothesis paper proposes that ventilation tuned within lung-protective limits might also preserve the mechanical signals needed for the ...

A new review grades Piezo1 mechanobiology evidence across eye compartments and proposes, as a hypothesis rather than an established pathway, ...

A new review outlines how glycine-based piezoelectric nanogenerators harvest electricity from body motion while being explored for supporting the regeneration ...

A mouse study finds that the collagen receptors β1 integrin and DDR2 cooperate to drive skeletal progenitor cell migration, proliferation ...

A new multi-level computational framework uses Brinkman continuum equations to efficiently model fluid and solid stresses in the porous, trabeculated ...

An integrated single-cell atlas of more than 375,000 endothelial cells from 12 human tissues identifies conserved transcriptional hallmarks of vascular ...

Keratin 9 restrains mechanical YAP1 signalling in palmoplantar skin, and experimental YAP1 inhibition reduced thickened epidermis in keratin 9-deficient mice.

A new review in Molecular Biology Reports unifies how mechanobiological cues at cellular adhesions drive cytoskeletal reconfiguration, with implications for ...

New research shows that Caveolin-1, the core protein of mechanosensitive caveolae, is concentrated in optic nerve head astrocytes and rises ...

A new mouse study reveals that the giant muscle protein titin acts as a mechanosensory hub in uterine smooth muscle, ...

New research shows that the nuclear envelope protein SUN2 regulates endothelial microtubule dynamics, focal adhesions, and extracellular matrix quality to ...

A conditional knockout study shows that deleting the mechanosensor YAP in stretched tendon cells disrupts a broad lipid-metabolism and immune-linked ...

A nanostructured gelatin hydrogel that dynamically reshapes itself around Schwann cells has enabled nerve conduit performance in rats rivaling autografts, ...

A new review in Reproductive Sciences proposes that tissue stiffness and mechanotransduction pathways may help explain the heterogeneity and progression ...

A new PLOS Biology study shows that the mechanosensitive ion channel Piezo1 allows oligodendrocytes to sense axon diameter and locally ...

A new review proposes that disturbed blood flow and metabolic stress converge to drive endothelial cell senescence, amplifying cardiometabolic vascular ...

A new study shows that low-intensity ultrasound combined with clinical microbubble agents reverses endothelial dysfunction and improves kidney function in ...

A new multimodal platform combines 3D tumor spheroids, rheology, and compression testing to fingerprint the viscoelastic stiffness of breast cancer ...

A new review redefines the primary cilium as a dynamic sensory-metabolic hub whose disruption contributes to cardiovascular, reproductive, metabolic, cancer ...

Researchers have created the first stable prostate cancer cell lines resistant to blood-flow-level shear stress and identified the calcium-buffering gene ...