Multicellular liver-on-a-chip for modeling fatty liver disease
Credit: Khademhosseini Lab (LOS ANGELES) - Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. It ...
Tag: Liver
Post-Fontan liver fibrosis goes under the radar
Osaka City University shows current diagnostic methodology for liver fibrosis does not accurately track the disease when it occurs as ...
Protein controlling magnesium identified as therapeutic target for non-alcoholic fatty liver disease
Patients with liver disease have significantly elevated expression of CNNM4 protein, which modulates magnesium in the liverCredit: CIC bioGUNE An ...
Many genes associated with the risk of coronary artery disease act through the liver
Credit: UEF/Raija Törrönen. According to a new study published in The American Journal of Human Genetics, more than one third ...
Going the distance–insights into how cancer cells spread
Credit: Kanazawa University Most tumors consist of a heterogenous mix of cells. Genetic mutations found only in some of these ...
An end to invasive biopsies?
Hebrew University researchers advance simple and inexpensive diagnostic blood testCredit: Hebrew University of Jerusalem In diagnostic medicine, biopsies, where a ...
Drug ‘breakthrough’ gives longest-ever survival in nonresectable liver cancer patients
The IMbrave150 trial found median overall survival was 19.2 months in patients treated with atezo+bev vs 13.4 months for those ...
Global survey reveals heavy toll of COVID-19 first wave on liver cancer care
The global Liver Cancer Outcomes in Covid-19 (CERO-19) Survey included 76 high-volume cancer treatment centres which participated during the first ...
New combination therapy offers chance of healing hepatitis B
Credit: CDC/Dr. Erskine Palmer The new therapeutic approach is based on shutting down the viral hepatitis B genome located in ...
Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
Credit: ©NAKANISHI Makoto, The Institute of Medical Science, The University of Tokyo(IMSUT) Senescent cells accumulate in organs during aging, promote ...
Our gut-brain connection
'Organs-on-a-chip' system sheds light on how bacteria in the human digestive tract may influence neurological diseasesCredit: Martin Trapecar, MIT CAMBRIDGE, ...
A stem cell based cell culture model for nonalcoholic fatty liver disease
Recent publication in Biology OpenCredit: Dr. Nina Graffmann, University Hospital Duesseldorf Nonalcoholic fatty liver disease (NAFLD) is a widespread condition ...
CT identifies patients with high-risk nonalcoholic fatty liver disease (NAFLD)
Multiparametric CT findings can distinguish patients with high-risk NAFLD (advanced fibrosis or cirrhosis); however, the presence of nonalcoholic steatohepatitis (NASH) ...
ACSL1 as a main catalyst of CoA conjugation of propionic acid-class NSAIDs in liver
Researchers from Kanazawa University find that propionic acid-class NSAIDs are conjugated with CoA by hepatic ACSL1, leading to liver toxicity ...