Zone 2 hepatocytes sense mechanical stress to drive liver regeneration via PIEZO1
A new study identifies DPP4-positive zone 2 hepatocytes as mechanosensory cells that trigger liver regeneration through PIEZO1-mediated mechanotransduction.
A new study identifies DPP4-positive zone 2 hepatocytes as mechanosensory cells that trigger liver regeneration through PIEZO1-mediated mechanotransduction.
A narrative review in BMC Pediatrics examines how the balance between regeneration and scarring breaks down in pediatric liver fibrosis, ...
A rat study finds that chronic high-fat diet feeding leaves liver organoid-forming regenerative cells locked in a senescence-like state with ...
A comparative study of rats and humans quantifies how somatic polyploidy, proliferation and hypertrophy each contribute to liver regeneration during ...
A phase 2 French trial shows that temporary portal vein embolization with absorbable gelatin safely induces clinically meaningful liver regrowth ...
A new review in Nature Reviews Gastroenterology & Hepatology explains how cholangiocyte primary cilia sense bile flow, chemistry and tonicity ...
New research shows that the bile acid receptor FXR coordinates monocyte recruitment and Kupffer cell proliferation through CCR2 and CSF1/PI3K/Akt ...
In a groundbreaking study published in Nature Metabolism, researchers have unveiled a critical metabolic checkpoint governing liver regeneration: the mitochondrial ...
Hepatic stellate cells (HSCs), once primarily recognized for their role in driving liver fibrosis, have emerged as crucial regulators of ...
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