Newly Found Oocyte Protein OMC1 Keeps Egg Chromosomes Cohesive for Life
Researchers identified OMC1, an oocyte-specific protein that maintains chromosome cohesion throughout reproductive life, and showed that its loss accelerates age-related ...
Tag: Knockout mice
Loss of CD47 Shifts Mouse Hippocampus Toward a Mild Stress-Like State
Single-nucleus RNA sequencing shows that Cd47 loss shifts the mouse hippocampal transcriptome toward a state resembling mild excitotoxic stress.
Losing cGAS Drives Microglial Decline and Progressive Neurodegeneration in Mice
A new mouse study finds that losing cGAS disrupts microglial homeostasis and drives progressive neurodegeneration from early adulthood.
Gene Loss Reshapes the Developing Mouse Cortex
Deleting Ptprd changes excitatory and inhibitory neuron markers and disrupts synaptic transmission in the postnatal mouse somatosensory cortex.
Scaffold Protein SH3BP2 Revealed as Key to Muscle Strength at the Neuromuscular Junction
Researchers have discovered that the scaffold protein SH3BP2, previously known for its role in immune and bone cells, is essential ...
Gender Differences in Anxiety and Depression in Mice
In recent years, there has been a growing interest in understanding the biological basis of sex differences in mental health ...
