Atypical GPCR Signaling Pathway Drives Heart Scarring, Stanford Team Finds
Cardiac fibrosis has long been viewed as one of the most stubborn problems in cardiovascular medicine, largely because the cells ...
Tag: iPSC
Patient-Derived Stem Cells Point to Muscle Gene Faults in ME/CFS and 21 Drug Repurposing Candidates
For millions of people living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, the search for answers has been a frustrating one. The ...
Silencing SLITRK2 Rescues Damaged Nerve-Muscle Connections in FUS-ALS Motor Neurons
Researchers found that reducing SLITRK2 levels in human stem cell-derived FUS-ALS motor neurons restores axonal health and neuromuscular junction signaling, ...
Brain organoids without immune cells may miss the real story of neurodegeneration
A PLOS Biology Perspective argues that immune and vascular cells, especially microglia, must be core components of neural organoids used ...
Scientists Map a Route to Rebuilding Damaged Airways With Engineered Cell Therapies
A new translational framework in the Journal of Translational Medicine integrates airway conditioning, biomaterials and epithelial cell therapies to overcome ...
Blood Cells Rewound: Direct Neural Conversion Slowly Erases Epigenetic Age
Direct conversion of human blood cells into neural stem cells erases nearly all epigenetic age over a protracted fifty-day process ...
Long-Read Genome Sequencing Powers a New, Deeply Characterized iPSC Resource for Lab Modeling
Researchers at the Coriell Institute have created a publicly available iPSC resource with HiFi long-read whole-genome sequencing, pharmacogenomic and HLA ...
Advancing T1D Cell Therapy Towards Clinical Implementation
In recent advancements in medical science, researchers have turned their attention to harnessing cell therapy as a potential solution for ...
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