Phase Separation Is an Evolvable Trait, Argues New Evolutionary Framework
A new perspective argues that liquid–liquid phase separation should be studied as an evolvable molecular phenotype shaped by natural selection.
Tag: intrinsically disordered regions
New open platform links molecular simulations to NMR data across the GPCRome
An open platform called GPCRmd-NMR combines molecular dynamics simulations with NMR spectroscopy to expose hidden conformational dynamics across more than ...
Machine Learning Reads Protein Disorder to Sort Autism Genes from the Rest
A new machine learning study shows that the amount of intrinsic disorder in a gene's protein product can help distinguish ...
Plants Build Their Own Sunscreen From Protein Condensates Under Intense Light
A Nature Plants highlight describes how singlet oxygen triggers MBS1 protein condensates that shield chloroplasts from excess light, and how ...
Unstructured Protein Segments: The Key to Regulating Biological Functions
In a groundbreaking study that promises to reshape our understanding of cellular signal transduction, researchers have unveiled the pivotal role ...
Unraveling Disordered Regions Driving mRNA Decay
Intrinsically disordered regions (IDRs) within proteins represent one of the most enigmatic frontiers of molecular biology. Unlike their well-structured counterparts, ...
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