Tag: inflammatory bowel disease

A five-year NIH-funded Mount Sinai study will examine associations between PFAS exposure, pre-diagnostic glycosylation changes and later inflammatory bowel disease ...

An observational study found hidden immune activity and a distinctive gut environment in bowel disease associated with PSC, offering a ...

A preclinical mouse study found that intraperitoneally delivered macrophages engineered to secrete IL-10 reduced disease activity, preserved colon length, and ...

A formulation combining a plant-derived Lactobacillus plantarum strain with a human-derived Lactobacillus fermentum strain reduced inflammation biomarkers and showed no ...

A macrophage-targeted TIMD4 peptide nanoparticle reduced inflammation and monocyte recruitment in a mouse colitis model without establishing clinical benefit in ...

A 2026 review identifies pyroptosis as a context-dependent pathway in intestinal and systemic inflammation and evaluates inflammasome, caspase and gasdermin-directed ...

A new mouse study shows banana starch nanoparticles worsen colitis by damaging tight junctions and disrupting gut microbes, while native ...

Researchers report that Y RNAs on the surface of human monocytes bind extracellular histones and amplify TLR2/TLR4-driven inflammatory signaling, with ...

A large-scale serology study presented at UEG Week 2026 found distinct antibody signatures up to ten years before an inflammatory ...

A new special issue in Frontiers in Pediatrics gathers ten peer-reviewed studies revealing how inflammatory bowel disease presents, is diagnosed, ...

A single-nuclei study reveals how CXCL14+ fibroblasts and SPP1+ macrophages form a collagen IV-driven feedback loop that promotes fibrosis and ...

Multi-omics study reveals how myeloid-derived IL6/JAK/STAT3 signaling creates a spatially organized immunosuppressive niche that drives colitis-associated carcinogenesis, offering a potential ...

A new study shows that the 1,800-year-old Chinese formula Baitouweng Tang relieves ulcerative colitis by reshaping gut microbiota and boosting ...

A neuroimaging study of 49 people with Crohn's disease links physical, cognitive, and psychosocial fatigue to distinct patterns of cortical ...

A new review argues that maladaptive sensory coding by intrinsic primary afferent neurons in the enteric nervous system may drive ...

Scientists engineered a probiotic bacterium that produces the anti-inflammatory lipid palmitoylethanolamide directly in the gut, protecting mice with chronic colitis ...

A real-world study from Abu Dhabi found that pairing two advanced therapies with different mechanisms achieved combined clinical and biochemical ...

The relationship between intestinal inflammation and behavioral changes has become one of the more compelling frontiers in gastroenterology and neuroscience ...

A landmark review reveals how artificial intelligence and integrative multi-omics are transforming host-microbiome research, converting complex molecular data into predictive ...

A bidirectional Mendelian randomization study shows that genetic liability to primary biliary cirrhosis causally raises the risk of ulcerative colitis, ...