Tag: Immunopeptidomics

Researchers mapped the functional architecture of human leukocyte antigens across 155 class I and 93 class II allotypes into 40 ...

A scientific review highlights how microproteins translated from previously overlooked short open reading frames regulate leukemogenesis and present novel targets ...

Brief antibody-mediated depletion of CD8+ T cells in aged APP/PS1 mice left amyloid plaques unchanged but reduced dystrophic neurites and ...

MSIPep combines immunopeptidomics, transcriptomics and deep learning to identify and computationally prioritize candidate tumor peptides in leukemia and solid-tumor datasets.

A new study finds that calreticulin, long considered an essential chaperone for MHC class I antigen presentation, is functionally expendable ...

A new review in Nature Reviews Cardiology lays out a framework for defining heart-specific T cell responses and the cardiac ...

Using mass spectrometry-based immunopeptidomics, researchers identified 57 MHC-II peptides from 23 Francisella tularensis proteins and pinpointed ten immunogenic CD4 T ...

A landmark Perspective in Nature Reviews Cancer argues that the cancer dark proteome — thousands of uncharacterized proteins from non-canonical ...

In a groundbreaking advance that could redefine tuberculosis (TB) vaccine development, researchers at the Massachusetts Institute of Technology have identified ...