Evidence for link between ‘leaky gut’ and autoantibody production in HIV-positive patients
Investigators at the Medical University of South Carolina report in Microbiome that autoantibody production in HIV-positive patients who have undergone ...
Tag: Immunology/Allergies/Asthma
Pitt research reveals how immune cells help tumors escape body’s defenses
PITTSBURGH, April 1, 2019 - New research from the University of Pittsburgh School of Medicine and the UPMC Hillman Cancer ...
HDAC inhibition may combat resistance to anti-PD-1 therapy in patients with melanoma
ATLANTA -- A combination of the experimental histone deacetylase (HDAC) inhibitor entinostat with the anti-PD-1 therapeutic pembrolizumab (Keytruda) showed clinical ...
Researchers discover how tumor-killing immune cells attack lymphomas in living mice
Credit: Cazaux et al., 2019 In a study that will be published April 1 in the Journal of Experimental Medicine, ...
Data from two KEYNOTE trials show pembrolizumab benefited patients with advanced SCLC
ATLANTA -- The anti-PD-1 monoclonal antibody pembrolizumab (Keytruda) showed promising antitumor activity with durable responses in patients with pretreated, advanced ...
New evidence about why clear margins in breast cancer surgery are such good news
Credit: Phil Jones, Senior Photographer, Augusta University AUGUSTA, Ga. (April 1, 2019) - When a breast cancer tumor is removed ...
New glioblastoma vaccine shows promising results in phase Ib clinical trial
A brain-cancer vaccine more than 20 years in the making suspends cancer growth in patients enrolled in early-stage trial. (PHILADELPHIA) ...
Immune checkpoint inhibitor combo efficacious for patients with neuroendocrine carcinoma
ATLANTA -- A combination of the anti-CTLA-4 immunotherapeutic ipilimumab (Yervoy) and the anti-PD-1 immunotherapeutic nivolumab (Opdivo) showed clinical benefit among ...
HER2-targeted CAR T-cell therapy shows promising antitumor activity in patients with sarcoma
ATLANTA -- A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2 was ...
Mesothelin-targeted CAR T-cell therapy shows early promise in patients with solid tumors
ATLANTA -- A chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major toxicity ...
UA immunobiologist will use $1.9 million grant to explore copper’s potential as antibiotic
Pneumonia starts like this: A bacterial cell called Streptococcus pneumoniae enters the nostril. It travels down the nasal passage and ...
Major step towards individual cancer immunotherapy
Cells belonging to the body's own immune system can help fight tumours. For several years now, this has allowed oncologists ...
Introducing a kinder, gentler way to blow holes in cells
For injecting CRISPR-Cas9 into cells, new technique is more efficient, simpler and cheaperCredit: Yuhong Cao, UC Berkeley When scientists attempt ...
Bacteria partners with virus to cause chronic wounds, Stanford study finds
A common bacterial pathogen called Pseudomonas aeruginosa produces a virus that substantially increases the pathogen's ability to infect us, according ...
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