Inhibiting ROCK2 Protects Platelets by Suppressing Destructive Cytotoxic T Cells
Targeting the kinase ROCK2 suppresses cytotoxic T lymphocyte activation and restores mitochondrial metabolism to prevent platelet destruction in primary immune ...
Tag: Immune thrombocytopenia
Derived metabolic indices and poor early response to corticosteroids in adults with primary immune thrombocytopenia: a retrospective cohort study
A retrospective cohort study found that higher pretreatment levels of derived metabolic indices are associated with a poor early response ...
HAE Patients Show No Distinct Autonomic Stress Response
A study in BioPsychoSocial Medicine found no distinct physiological stress responses in hereditary angioedema patients compared to those with immune ...
Half of Children with Immune Thrombocytopenia Show Zinc Deficiency, Study Finds
A cross-sectional study of 74 Egyptian children and adolescents with primary immune thrombocytopenia found zinc deficiency in half of patients ...
Immune Cells Skew Toward Inflammation in Children With Newly Diagnosed ITP
A case-control study of 32 children with newly diagnosed immune thrombocytopenia found a pro-inflammatory shift in circulating monocyte-macrophage polarization and ...
Delayed dengue-associated hemorrhagic pericarditis with cardiac tamponade in elderly patient
A single-patient case report links delayed hemorrhagic fibrinous pericarditis and cardiac tamponade to recent dengue infection in an 88-year-old woman ...
Broncholith Removal Using a Cryoprobe in Combination With Biopsy Forceps in a Patient With Immune Thrombocytopenia: A Case Report
A case report describes how a flexible bronchoscope, a freezing cryoprobe and gentle biopsy forceps were used to extract a ...
Age linked to long-term ITP risk in 910-child cohort
A retrospective study of 910 children with immune thrombocytopenia linked age, bleeding severity and glucocorticoid-tapering duration with initial treatment response ...
FAS and FASL Blood Tests Fall Short as Diagnostic Biomarkers for Autoimmune Lymphoproliferative Syndrome
A new study finds that whole-blood FAS and FASL mRNA expression cannot reliably distinguish autoimmune lymphoproliferative syndrome from immune thrombocytopenia, ...
IGF1R Elevation and Methylation Alterations in ITP
Elevated levels of insulin-like growth factor 1 receptor (IGF1R) in immune thrombocytopenia (ITP) pose a significant avenue for exploration in ...
