Tag: immune evasion

A new review in Cancer Reports proposes that the extracellular matrix protein COL6A1, overexpressed in the fibrotic stroma of cholangiocarcinoma, ...

A pan-cancer single-cell atlas of nearly 900,000 cells shows that bone metastases from ten cancer types share convergent malignant programs ...

A new review in the Journal of Translational Medicine details how RGS proteins, the off switches of GPCR signaling, reshape ...

A bioinformatic study links the spindle checkpoint kinase TTK to poor survival and immune evasion in lung adenocarcinoma through a ...

By combining spatial and single-cell transcriptomics, researchers have mapped previously unknown immunosuppressive niches in colorectal cancer, including SPP1-positive macrophage rings ...

Researchers identified a fish-specific E3 ubiquitin ligase, NHRE3, that suppresses antiviral immunity in grass carp and rare minnows by tagging ...

A new PLOS Biology study of fluconazole-resistant Candida parapsilosis outbreak isolates shows that strains with reduced biofilm production gain metabolic ...

Researchers report that Ailanthus excelsa quassinoids delivered in chitosan nanoparticles suppress STAT3-driven PD-L1 transcription and restore T-cell antitumor activity in ...

Plasma-derived small extracellular vesicles from head and neck cancer patients suppress T-cell proliferation, trigger apoptosis, and rewire immune checkpoint expression ...

A new review in Medical Oncology maps how the tumor microenvironment can either amplify or suppress ferroptosis, the iron-dependent cell ...

A new review details how the matrix protein SPP1 orchestrates immunosuppression across the tumor microenvironment and outlines emerging strategies to ...

A new review describes how NMDA glutamate receptors on myeloid cells drive calcium-dependent reprogramming toward immunosuppressive states, and how blocking ...

A new review in the Journal of Translational Medicine proposes that the physical mechanics of solid tumors govern whether mitochondrial ...

A new analysis suggests HIV impairs the immune system's ability to recognize tumor neoantigens in non-small cell lung cancer without ...

A new systematic review and meta-analysis of 20 human studies finds no consistent association between root canal bacteria and breast ...

A sweeping new review maps how the epithelial guardian protein MUC1, and especially its MUC1-C signaling subunit, is hijacked by ...

In a groundbreaking study poised to reshape our understanding of colorectal cancer and its interaction with the immune system, researchers ...

In an increasingly cancer-conscious world, new research findings are pointing towards a promising therapeutic strategy to tackle one of the ...

Chimeric Antigen Receptor T-Cell Therapy: A Revolutionary Approach to Chronic Viral Infections Chronic viral infections pose significant challenges to global ...

Recent research has unveiled the profound role of interleukin-6 (IL-6) in the polarization of Dectin-1 macrophages, offering new insights into ...