Fluorescent Reporter System Boosts Prime Editing Efficiency in Stem Cells
A new protocol details PINE-TREE, a transient fluorescent reporter system that enriches prime-edited human pluripotent stem cells and yields up ...
Tag: human pluripotent stem cells
Scientists Build Blood Vessel Organoids in Six Days Using Genetic Programming
A new protocol generates tunable human vascular organoids in six days by inducibly activating the transcription factors ETV2 and NKX3.1 ...
Seven-Chemical Cocktail Rewinds Human Stem Cells to an Eight-Cell Embryonic State
Researchers report that a seven-chemical cocktail rapidly converts human pluripotent stem cells into 8-cell-like cells that transcriptionally and functionally mirror ...
From Dish to Living Brain: How Lab-Grown Human Microglia Are Rewriting Neuroimmune Research
A new review charts how stem cell-derived human microglia, brain organoids and chimeric mice are overcoming the genetic and environmental ...
Mini Blood Vessels in a Miniature Plate: 96-Well Platform Streamlines Organoid Production
Researchers in China have adapted blood vessel organoid production to a 96-well ultra-low-attachment plate, enabling independent, cost-effective, and higher-throughput vascular ...
Creating Patterned Human Neural Tube Structures with Microfluidics
Recent advances in biomedical research have unveiled the complex processes that underlie neural development, particularly focusing on how the embryonic ...
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