A Hidden Brain Enzyme Emerges as the Secret Weapon Against Memory Decline in Aging
Scientists have discovered that an aging-induced secreted phospholipase called PLA2G2F acts as a neuron-derived signal that protects synapses, calms inflammatory ...
Scientists have discovered that an aging-induced secreted phospholipase called PLA2G2F acts as a neuron-derived signal that protects synapses, calms inflammatory ...
Researchers have refined a decades-old method for keeping intact mouse hippocampal slices alive for weeks, enabling precise quantification of newborn ...
A new mouse study shows that electroconvulsive treatment can drive hippocampal neurons back to an immature state only from about ...
Researchers report that suppressing the lipid-metabolizing enzyme PLA2G7 in hippocampal neural stem cells restores inhibitory synapses and improves memory in ...
A new mouse study shows that early chronic cerebral hypoperfusion spatially biases tau pathology and drives neuroinflammation at the onset ...
Weekly diffusion MRI during six weeks of partial-brain radiation therapy for high-grade glioma reveals a progressive, dose-dependent increase in hippocampal ...
Chronic inhibition of the enzyme soluble epoxide hydrolase with TPPU restored memory, cerebral blood flow, blood-brain barrier integrity, and neuronal ...
A new rat study shows that resveratrol slows epilepsy development and protects the hippocampus by restoring SIRT1 signaling and rebalancing ...
A new study in iScience shows that blocking the cannabinoid CB1 receptor with low-dose rimonabant reverses disease-associated alternative splicing defects ...
A landmark autopsy study of 2,550 brains shows APOE-ε4 drives medial temporal tau through amyloid-β while women's tau burden persists ...
A new review reveals that the dynamic expression of estrogen receptor subtypes across brain development may explain why anesthesia causes ...
A new exploratory RNA sequencing study finds that the hippocampal response to anesthesia and surgery is directionally inverted in 5xFAD ...
A new review maps how the kappa-opioid receptor/dynorphin system acts as a circuit-specific switch in the brain's fear and reward ...
A multimodal MRI study shows that type 2 diabetes patients with cerebral small vessel disease exhibit measurable white matter damage ...
Harvard researchers used tissue-like flexible electrode arrays to track the same mouse neurons for five months and showed that geometric ...
A new review in Molecular Biology Reports details how the polyphenol resveratrol may protect and enhance synaptic plasticity through antioxidant, ...
In an intriguing development within the field of neuroscience and gut health, recent research indicates that fecal microbiota transplantation (FMT) ...
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