Lactate Fuels a Hidden Molecular Chain That Helps Liver Cancer Evade Immunity
A new study reveals how lactate-driven lactylation of histone and non-histone proteins in liver cancer activates a METTL3-FDFT1 cholesterol pathway ...
A new study reveals how lactate-driven lactylation of histone and non-histone proteins in liver cancer activates a METTL3-FDFT1 cholesterol pathway ...
A new rat study in BMC Cancer reports that curcumin and piperine, especially in combination, prevent chemically induced hepatocellular carcinoma ...
Researchers have used dimensionless scaling laws and multiphysics simulations to design catheter-based magnetic filters that could capture excess chemotherapy drugs ...
A large community study in Guangzhou found that hepatitis knowledge alone did not predict follow-up adherence among screening-positive patients, with ...
Researchers have identified a stress-responsive subset of MAIT cells that promotes an immunosuppressive peritumoral environment and microvascular invasion in hepatocellular ...
Researchers combined anti-PD-L1 immunotherapy with the PARP inhibitor Olaparib to trigger ferroptosis in liver cancer and used the SLC7A11-targeted PET ...
A multi-omics study of 194 liver cancer patients shows that lenvatinib blood concentrations above 26.5 ng/mL predict treatment response, while ...
New research reveals that the ubiquitin-editing enzyme A20 promotes the degradation of the pro-tumor protein osteopontin in hepatocellular carcinoma, offering ...
A phase II pilot trial found that a single fecal microbiota transplantation combined with atezolizumab and bevacizumab was safe and ...
A new study shows that the long noncoding RNA SNHG15 drives hepatocellular carcinoma progression by scaffolding the PGK1-PDK1-PDHE1α phosphorylation axis ...
Researchers report that loss of the tumor suppressor LZTR1 stabilizes mitochondrial transcription factor A, reprogramming liver cancer cells toward complex ...
A multicenter study shows that grading the severity of microvascular invasion in resected liver tumors strongly predicts recurrence and survival ...
Whole-exome sequencing of liver transplant patients with hepatocellular carcinoma has identified a 13-gene mutation signature that independently predicts tumor recurrence ...
A new review in the Journal of Translational Medicine maps how perineural invasion may drive hepatocellular carcinoma aggression, organizing the ...
Veterinarians report a rare case of left medial liver lobe torsion associated with hepatocellular carcinoma in a 12-year-old Pembroke Welsh ...
New preclinical research shows that the plant compound coumarin activates natural killer cells, boosts their mitochondrial energy supply, and shrinks ...
Researchers in China have shown that the deubiquitinating enzyme USP45 promotes hepatocellular carcinoma progression by removing K48-linked ubiquitin chains from ...
A Taiwanese preliminary study found that following a short course of immune checkpoint inhibitors with infusions of tumor-primed dendritic cells ...
A meta-analysis of 34 studies covering over 4.2 million people finds that high adherence to the Mediterranean diet is associated ...
A 2023 review from Fudan University documents how Chinese clinical trials and single-cell omics studies are transforming the treatment and ...
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