Liver Injury After CAR T-Cell Therapy May Be Driven by Cytokine Storm, Landmark Analysis Finds
A pharmacovigilance analysis of nearly five million adverse-event reports finds that liver injury after CAR T-cell therapy is predominantly early ...
Tag: Hematology
Fat-Processing Gene Variants Tied to Lymphoma Risk and Survival
A Chinese genetic association study links inherited variants in lipid metabolism genes to the risk, severity, treatment response, and survival ...
Rare Cold-Triggered Anemia Strikes After Shingles and COVID-19 in First Reported Case
A 69-year-old man developed severe paroxysmal cold hemoglobinuria following shingles and COVID-19, in what researchers report as the first case ...
Waiting Longer for Lymphoma Treatment May Not Shorten Survival, Nationwide Study Finds
A nationwide German registry study of more than 16,000 diffuse large B-cell lymphoma patients found that later initiation of immunochemotherapy ...
Organ Failure Trajectories Offer Limited Prognostic Clues in Transplant Patients in the ICU
A French retrospective study of 161 allogeneic hematopoietic cell transplantation recipients finds that day three SOFA scores and new organ ...
Routine Blood Tests Reveal Distinct Fingerprints Across 29 Infection Types in Study of 455,530 Patients
A large-scale analysis of 455,530 infection patients shows that routine blood count parameters form distinct site-associated patterns across 29 infection ...
Life After the Pill: Real-World Quality of Life Across CML Drugs and Treatment-Free Remission
A nationwide Israeli survey of 233 CML patients finds overall quality of life is preserved across tyrosine kinase inhibitors, but ...
Routine Blood Test Marker RDW Linked to Higher Hip Fracture Risk in Older Adults
A large UK Biobank cohort study finds that higher red blood cell distribution width, a routine blood count measure, is ...
Modest Spleen Shrinkage Plus Transfusion Freedom Predicts Longer Survival in Myelofibrosis Patients on Momelotinib
Post hoc analyses of the SIMPLIFY-1 and MOMENTUM phase 3 trials show that myelofibrosis patients treated with momelotinib who achieve ...
Expert Panel Maps the Hidden Variables That Could Skew CAR-T Comparisons in Lymphoma
A two-round expert elicitation among German and Austrian hematologists has produced a consensus list of prognostic factors and treatment-effect modifiers ...
Giant Muscle Gene Titin Emerges as a Driver of Drug-Resistant Childhood Leukemia
A study of 152 Chinese children with acute lymphoblastic leukemia links mutations in the titin gene to prednisone resistance, poor ...
Blood Cancer Risk After CAR-T and Stem Cell Transplants: Systematic Review Maps Latency and Clonal Drivers
A systematic review of nine studies finds that therapy-related myeloid neoplasms after CAR-T therapy emerge earlier and carry worse survival ...
Female Donors Raise Graft-Versus-Host Disease Risk in Male Recipients, Meta-Analysis Confirms
A new systematic review and meta-analysis finds that female donor-to-male recipient transplantation significantly increases the risk of moderate-to-severe acute graft-versus-host ...
Engineers find imaging technique could become treatment for deep vein thrombosis
Credit: Penn State/Scott Medina Penn State College of Engineering researchers set out to develop technology capable of localizing and imaging ...
McMaster researchers identify how VITT happens
The work will have both diagnostic and therapeutic implicationsCredit: James Smith/McMaster University Hamilton, ON (July 7, 2021) - A McMaster ...
JNCCN study recommends improvements for cancer care at network sites
A 27-question survey of Association of American Cancer Institutes (AACI) members, including many NCI-designated centers, identified several opportunities to improve ...
Unraveling the mechanisms that create the individualized metabolism in leukemia
Credit: Associate Professor Shinjiro Hino A research collaboration based in Kumamoto University (Japan) has shown that lysine-specific demethylase 1 (LSD1), ...
Pumped to assist the heart with an artificial aorta
In January of this year, EPFL engineers announced in Advanced Science their concept of a novel cardiac assist device that ...
Blood clots related to AstraZeneca/Oxford vaccine can be mitigated with early detection
New research highlights the need for heightened awareness and early testing for patients with signs of clotting disorder following vaccination ...
Microfilter device capable of detecting trace amounts of cancer cells in one mL of blood
Top: The device is small enough to fit in the palm of your hand. A microfilter device that can easily ...
