Scientists define the role for a rare, influential set of bone marrow cells
Researchers have defined the roles of various cells in the bone marrow that are thought to control the fate of ...
Tag: Hematology
Advance in CAR T-cell therapy eliminates severe side effects
USC-led clinical trial produced remissions without toxicity in lymphoma patients An advance in the breakthrough cancer treatment known as CAR ...
Overlooked molecular machine in cell nucleus may hold key to treating aggressive leukemia
Spliceosome misconnects generate mutant gene/protein that fuel cancerous cellsCredit: Cincinnati Children's CINCINNATI - Many individuals forced to fight an exceptionally ...
Management and outcomes of aortic dissection in pregnancy with Marfan Syndrome
This article by Dr. Ayman El-Menyarand et al. is published in Current Vascular Pharmacology, 2019 Hemodynamic adaptations taking place during ...
Gene-based factor VIIa prevents bleeding episodes in animals with hemophilia
CHOP researchers: Preclinical work offers first target levels for bypass agent prophylaxis in future human trialsCredit: Children's Hospital of Philadelphia ...
CD30: From witness to culprit
The study, which was supported by the German Cancer Aid, suggests that vaccination against EBV might reduce the risk of ...
Identification of lymph node cells that may play important roles in immune tolerance
Credit: Kanazawa University The thymus is the organ in which T cells*1) differentiate. T cells express various T cell receptors ...
Specific criteria needed for different types of myeloma
Credit: Phil Jones, Senior Photographer, Augusta University AUGUSTA, Ga. (April 8, 2019) - When our plasma cells start producing a ...
Mount Sinai researchers develop treatment that turns tumors into cancer vaccine factories
(New York, NY - April 8, 2019) -- Researchers at Mount Sinai have developed a novel approach to cancer immunotherapy, ...
Immune cells fighting blood cancer visualized for the first time
When cancer escapes the immune system, our defenses are rendered powerless and are unable to fight against the disease. Chimeric ...
Older adults with blood cancers: How they fare
Although the majority of patients who have blood cancers are older adults, they make up only a small percentage of ...
Mutation stands in the way of healthy blood cell maturation
In the veins, stem cells constantly mature and develop into different blood cells that are necessary for the body to ...
The decline of state-level IVC filter utilization
Medicare and private insurance analysis After a period of prior growth, national inferior vena cava (IVC) filter utilization in the ...
2019 Harrington Prize awarded to Dr. Carl June, University of Pennsylvania
Harrington Discovery Institute and the American Society for Clinical Investigation honor Dr. June for his contributions to the field of ...
Evidence for link between ‘leaky gut’ and autoantibody production in HIV-positive patients
Investigators at the Medical University of South Carolina report in Microbiome that autoantibody production in HIV-positive patients who have undergone ...
Researchers at Dana-Farber/Boston Children’s optimize gene editing for SCD and beta thalassemia
New strategy for editing blood stem cells is more efficient and targetedCredit: Daniel Bauer/Boston Children's Hospital Researchers at Dana-Farber/Boston Children's ...
Southern Europeans, non-Europeans less likely to have matched stem cell donors
Alternative donor transplants are needed for these patients (WASHINGTON, March 27, 2019) -- Although the pool of registered bone marrow ...
Squishing blood stem cells could facilitate harvest for transplants
Knockout of Ptpn21 alters deformabilityCredit: From Ni et al Cell Stem Cell (2019) Scientists at Winship Cancer Institute of Emory ...
How ‘sleeper cell’ cancer stem cells are maintained in chronic myelogenous leukemia
This knowledge offers a strategy to target and eliminate these persistent leukemic stem cellsCredit: UAB BIRMINGHAM, Ala. - Most patients ...
Study gives new perspective on production of blood cells and immune cells
Researchers tracked and quantified the production of different kinds of blood cells and immune cells to understand how the body ...