Tag: Genomics

Researchers introduced b-move, a run-length compressed index that accelerates lossless approximate pattern matching in pan-genomes by up to seven times ...

An exploratory study of 19 Algerian patients with Parkinson’s disease identified rare variants in six candidate genes, highlighting the genetic ...

A multivariate genome-wide association study identifies shared genetic liability between obstructive sleep apnea and cardiometabolic traits, highlighting neuronal regulatory programs.

A scientific review highlights how computational linguistics, statistical laws, and formal grammars help decode regulatory patterns across noncoding genomic sequences.

A large sequencing study of infertile men identified recurrent X chromosome deletions and duplications as candidate genomic disorder loci, with ...

Researchers using ENCODE candidate cis-regulatory elements identified 136 non-coding loci capturing 699 rare-variant associations across 20 complex traits in whole-genome ...

Engineered algorithms identify strongly unique genomic k-mers in seconds across billions of sequences, substantially accelerating alignment-free sequence analysis and xenograft ...

A new network analysis framework identifies underexplored bridging genes in rheumatoid arthritis that coordinate immune-related processes.

Single-cell genomics reveals that soybean red crown rot is associated with the enrichment of Enterobacterales bacteria carrying genes for resistance ...

A narrative review in Genes and Environment finds that the APOE ε4 allele's risk for Alzheimer's disease is less pronounced ...

A systematic benchmark reveals that biologically structured module representations offer feature stability across breast cancer datasets without consistently outperforming gene-level ...

Scientists have discovered that marsupials maintain functional, expressed retrocopies of the essential DNA repair gene MLH1 to compensate for parent-of-origin ...

A scientific review details how genomic regulation, metabolic pathways, and modern breeding tools can improve antioxidant compounds in rice bran ...

EnzyREx, an AI-based framework with two deep learning models, identified candidate proteins for 897 of 1,255 microbiome-related orphan reactions.

Researchers developed an interpretable XGBoost-SHAP framework to prioritize noncoding variants and identify nonlinear regulatory interactions affecting HNF4A binding in pancreatic ...

Researchers have characterized bacteriophage vB_KpBD_211, a strictly lytic virus demonstrating potent antibiofilm and antibacterial activity against multidrug-resistant Klebsiella pneumoniae.

Researchers have identified a prehistoric BRCA1 founder variant in Rwandan breast cancer cases that originated thousands of years ago.

Researchers have sequenced the chromosome-level genome of the sea cucumber Holothuria glaberrima, identifying gene family expansions and transposable element dynamics ...

Researchers have developed SAIGE-QTL, an efficient Poisson mixed-model framework that directly analyzes single-cell read counts to substantially expand expression quantitative ...

A comprehensive genomic evaluation of rare Salmonella enterica serovar Inganda isolates demonstrates widespread antimicrobial susceptibility alongside preserved virulence determinants and ...