SmartPE boosts prime editing efficiency in dicot crops
A new gene-editing system called SmartPE improves prime editing efficiency in dicot plants like tomatoes and soybeans by introducing specific ...
Tag: Gene editing
CRISPR Advances Reshape Ornamental Crop Breeding and Global Floriculture Regulations
A comprehensive scientific review outlines how CRISPR-mediated genome editing overcomes longstanding genetic hurdles in ornamental crops while navigating divergent international ...
CRISPR Beta-Cell Regeneration Shows Early Promise for Long-Term Diabetes Management
A scientific review details how CRISPR-Cas9 gene editing is advancing through preclinical models and early clinical trials to regenerate insulin-producing ...
Extracellular Vesicles Show Dual Roles and Therapeutic Potential in Hearing Loss
A scientific review highlights how extracellular vesicles mediate inner ear damage and protection while offering potential biomarker and therapeutic applications ...
CRISPR Gene Therapy for Sickle Cell and Thalassemia Shows Strong Efficacy, but Long-Term Safety Questions Remain
A systematic review of 21 studies finds CRISPR/Cas9 therapies for beta-thalassemia and sickle cell disease achieve high transfusion independence and ...
Ultrasound and Light Guide Gene Editing to Selected Sites in Mouse Brains
A light-sensitive Cas12f editor and ultrasound-triggered nanoparticles enabled researchers to control gene disruption at a selected location in mouse brains.
European Consumers Fear Pesticides More Than Gene-Edited Watermelon, Survey Finds
A survey of 1,218 consumers in Spain, Germany and the UK found that conventional pesticides draw stronger rejection than precision-bred ...
CRISPR/Cas9 Disruption of oca2 and tyr Genes Alters Pigmentation in Zebrafish
Scientists used CRISPR/Cas9 to disrupt the tyr and oca2 pigmentation genes in zebrafish, reducing melanophores and visibly altering coloration in ...
CAR-NK Cells Move From Concept Toward Clinic as Review Maps Engineering Fixes
A new review synthesizes engineering strategies and early clinical findings for CAR-NK cell immunotherapy in blood cancers and solid tumors.
Four Amino Acids Explain Why Wild Tomatoes Outsmart Their Deadliest Pest
An international study shows that changing four amino acids in a single tomato enzyme flips the 3D shape of a ...
Patients weigh promise and peril of gene therapies for inherited heart disease
A qualitative study of 21 adults with familial cardiomyopathy finds that perceived disease severity, family history and safety uncertainties shape ...
Gene Editing Moves Toward Common Diseases as Cardiologists Urge Stronger Safeguards
University of Michigan cardiologists propose a five-question clinical framework for deciding when permanent genomic therapies are justified as gene editing ...
AI-Designed Gene Editor Helps Rice Resist Bacterial Blight
University of Missouri researchers used the AI-designed, open-source gene editor OpenCRISPR-1 to create rice plants that resist bacterial blight, with ...
Maize transcription factor ZmHY5L shapes waxy gene starch quality and grain size
A Yunnan landrace study identifies ZmHY5L as a G-box-binding activator of the maize waxy gene that influences endosperm starch quality ...
Pioneering Cardiac Xenotransplantation: Bridging Mortality in Pediatric Heart Disease
This review examines the clinical outcomes, pediatric preclinical evidence, and ethical considerations relevant to candidate selection for pediatric cardiac xenotransplantation, ...
Beyond the classics: why biology’s future lies in non-traditional model organisms
A BMC Biology editorial argues that falling costs in sequencing, imaging and gene editing are freeing biologists to study any ...
Review links Indian rice landrace diversity to low-glycemic traits
A review identifies starch structure, the waxy gene, resistant starch and grain-matrix interactions as molecular routes toward lower-glycemic-index rice, with ...
FsMP co-transformation achieves 95% leaf transformation in optimized Forsythia hairy-root protocol
An experimental protocol study achieved 95% leaf transformation efficiency in Forsythia suspensa through FsMP co-transformation in an optimized hairy-root system.
Engineered human AGO2 enables targeted C-to-U RNA editing in cells
Engineered human AGO2 and a C-to-U deaminase produced average messenger RNA editing 1.9-fold higher than two Cas13 comparators in HEK293T ...
Genetic map of osteogenesis imperfecta guides precision care
A review finds that genetically distinct forms of osteogenesis imperfecta require molecular diagnosis, subtype-aware treatment and combined orthopedic, medical and ...
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