Tag: Fibrosis

A small observational study found that serum CXCL-10 and CTLA-4 were associated with HBV viral load and histological inflammation in ...

Singapore's A*STAR has signed a Memorandum of Understanding with AI digital pathology firm HistoIndex to quantitatively evaluate preclinical therapeutic candidates ...

A drop of saliva, an infrared spectrometer, and a machine learning algorithm may be enough to flag oral submucous fibrosis, ...

Chronic kidney disease is a slow-motion catastrophe. Millions of people live with kidneys that are quietly being replaced by scar ...

A new study identifies miR-145 as a driver and biomarker of the fibrotic tumor microenvironment, linking NOTCH signaling, promoter hypomethylation, ...

Diabetic retinopathy has long been treated in clinics as a disease of leaky blood vessels, but a new review argues ...

Deep inside every chronically failing kidney, a quiet molecular drama unfolds. Scar tissue slowly strangles the delicate architecture of the ...

A new systematic review finds that evidence linking the oral bacterium Fusobacterium nucleatum to endometriosis is biologically plausible but conflicting, ...

A single-nuclei study reveals how CXCL14+ fibroblasts and SPP1+ macrophages form a collagen IV-driven feedback loop that promotes fibrosis and ...

A new study in Frontiers in Pharmacology suggests that the natural flavonoid rutin binds the splicing factor hnRNP L, interferes ...

A three-cohort transcriptomic reanalysis finds extracellular-matrix remodeling as the most reproducible molecular signature of frozen shoulder, while pyroptosis, ferroptosis, and ...

New research shows that the pro-fibrotic signal BMP4 drives mitochondrial dysfunction in kidney mesangial cells by suppressing Parkin, a key ...

A new study shows that hypertensive stress rewires cardiac macrophage signaling, impairing metabolic support for heart muscle cells while driving ...

A study of 511 endurance athletes and hypertensive patients finds that fibrosis biomarkers, especially galectin-3, are elevated in hypertension and ...

New research shows that dermoscopic vascular patterns visible before treatment can predict which keloids will respond to corticosteroid injections, with ...

A new review argues that inflammasome-derived molecular biomarkers could predict wound outcomes, distinguish healing from chronic inflammation, and guide precision ...

A proteomic study of ovaries from 28 women shows the postmenopausal ovary remains biologically active for decades, with mounting inflammation, ...

A new review maps how the peptide hormone adropin, once seen as a simple metabolic signal, orchestrates vascular, neurological, fibrotic, ...

An international study of more than 9,300 children across 17 countries finds that fatty liver disease affects about one in ...

Researchers in Dublin report that the enzyme autotaxin and its lipid product lysophosphatidic acid drive fibrosis in lamina cribrosa cells ...