Tag: Epigenetic reprogramming

A new study shows that SMARCAL1 forms nuclear condensates that reprogram chromatin and methionine metabolism, weakening radiotherapy and immunotherapy responses.

A new review proposes that mature tumor cells can dedifferentiate into cancer stem cells, acting as a non-genetic engine of ...

A new perspective argues that antigen-presenting fibroblasts in gastrointestinal tumors are reversible states whose immune role depends on unmeasured co-stimulatory ...

A new review in Epigenetics & Chromatin argues that incomplete epigenetic reprogramming remains the main barrier to efficient mammalian cloning ...

A new review outlines how drug-tolerant persister cells hidden within minimal residual disease drive cancer relapse and how pathway inhibitors, ...

A new review synthesizes evidence that maternal high-fat diet before and during pregnancy may program offspring coronary artery disease risk ...

A new research topic in Frontiers in Cell and Developmental Biology brings together studies on zygotic genome activation, epigenetic reprogramming, ...

A new review in the Journal of Molecular Medicine explains how trained immunity, driven by epigenetic and metabolic reprogramming of ...

A comprehensive review in Cell Death Discovery maps how the transcription factor Snail2 governs partial epithelial-mesenchymal transition, driving both embryonic ...

A new review explains how tumor cells reversibly switch identities through epigenetic and microenvironmental programs, driving metastasis and therapy resistance.

A sweeping new review maps how the epithelial guardian protein MUC1, and especially its MUC1-C signaling subunit, is hijacked by ...

In a stunning leap forward for immunotherapy, researchers from the Arc Institute, Gladstone Institutes, and the University of California, San ...

Researchers have developed an innovative laboratory model that promises to revolutionize the study and treatment of myelodysplastic syndrome (MDS), an ...