Biologic Therapy May Reshape Blood Clot Risk in Hidradenitis Suppurativa Over Time
A new retrospective study examines how venous thromboembolism risk changes over the course of biologic therapy in patients with hidradenitis ...
Tag: Endothelial dysfunction
STK39 Emerges as a Molecular Clue in Moyamoya Disease Under Hypoxic Stress
A new study links the kinase gene STK39 to endothelial dysfunction and inflammatory activation under hypoxic conditions in moyamoya disease, ...
USP28 enzyme drives deadly blood vessel damage in sepsis, mouse study reveals
Researchers identify a USP28–NMMHC IIA signaling loop that accelerates endothelial cell death and multi-organ injury in septic mice, revealing a ...
Hidden Vascular Flaw in PCOS Emerges Only When Blood Sugar Rises
Endothelial cells derived from women with PCOS harbor a latent mitochondrial defect that hyperglycemia unmasks, and blocking the enzyme myeloperoxidase ...
How Plant Polyphenols May Slow the Arterial Damage Behind Heart Attacks and Stroke
A new review in Molecular Biology Reports maps how dietary polyphenols such as resveratrol, quercetin, catechins, curcumin and anthocyanins target ...
Sepsis May Leave Tissues Primed for Cancer, Review Argues
A new review in the Journal of Translational Medicine argues that sepsis may remodel tissues through an Immuno–Vascular–Matrix Triad in ...
Itchy Skin Disease Linked to Higher Rates of Erectile Dysfunction in Large US Study
A large NIH All of Us analysis found that men with prurigo nodularis had significantly higher odds of erectile dysfunction, ...
Gentle Ultrasound and Microbubbles Repair Diabetic Kidney Damage in Mice
A new study shows that low-intensity ultrasound combined with clinical microbubble agents reverses endothelial dysfunction and improves kidney function in ...
Blood Fats and Fat-Cell Hormones Join Forces to Predict Diabetic Eye Disease
Researchers in China built a prediction model combining adipokines such as omentin-1 and adiponectin with red cell distribution width and ...
Calpain Blocker Restores Cellular Cleanup Crew and Protects Blood Vessels in Diabetes
A new study shows that overactivated calpains block autophagy and mitophagy in endothelial cells under high glucose, and that inhibiting ...
Endothelial Angptl2 Emerges as Central Driver of Influenza-Linked Lung Fibrosis
New research identifies endothelial Angptl2 as a key molecular driver linking influenza-induced vascular injury to pulmonary fibrosis through EndMT and ...
Mint Compound L-Carvone Shows Promise Against Uremia-Driven Blood Vessel Damage in Kidney Disease
Brazilian researchers report that the spearmint-derived monoterpene L-carvone reduced inflammatory biomarkers, monocyte recruitment, and structural damage in human endothelial cells ...
LncRNA PVT1 Influences Endothelial Function in DVT
In a groundbreaking study that could reshape our understanding of vascular health, researchers have meticulously dissected the role of long ...
Endothelial Dysfunction Tied to Post-COVID-19 Symptoms
In the wake of the COVID-19 pandemic, researchers have increasingly focused on the long-term health consequences associated with the virus. ...
IL-1β+ Lung Macrophages Drive Sepsis Lung Injury
In a groundbreaking study that promises to reshape our understanding of sepsis-induced lung injury, researchers have unveiled the critical role ...
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