Tag: Diabetic kidney disease

A systematic review of 14 economic evaluations across 12 countries finds dapagliflozin plus standard care may be cost-effective or dominant ...

A new review evaluates preclinical evidence that adipose-derived stem cell extracellular vesicles could multitarget the pathological processes driving diabetic microangiopathy.

A new review reframes diabetic kidney disease as a network-level disease driven by metabolites acting as signaling mediators, biomarkers and ...

An exploratory genomic framework combining Mendelian randomization, kidney-compartment eQTL data, and colocalization identifies seven candidate genes for kidney traits, with ...

A new review maps how natural products and traditional Chinese medicines may ease diabetic kidney disease by reshaping gut microbiota, ...

An outcome-blind clustering analysis of 6,667 adults with type 2 diabetes and diabetic kidney disease identified three clinical phenotypes with ...

A new narrative review proposes that exercise-responsive microRNAs, including the miR-34a–Klotho, miR-296-5p–SGLT2, and miR-126/Nrf2 axes, may help explain how exercise ...

A preclinical study reports that berberine reduced kidney injury in diabetic mice and curbed glucose uptake in kidney cells through ...

Urinary succinate levels are significantly elevated in patients with type 2 diabetes mellitus, particularly those with diabetic kidney disease, and ...

A prospective analysis of 9,963 UK Biobank participants found that closer residence to chemical plants was associated with higher risks ...

A narrative review assembles preclinical evidence that lactate signaling and lysine lactylation may connect metabolic reprogramming, inflammation and fibrosis in ...

A three-year retrospective analysis of US electronic health records found that people with insulin-treated diabetes and chronic kidney disease or ...

In a mouse model and cultured mesangial cells, tRF-15:31 reduced oxidative stress and inflammation through an SFRS1-linked mechanism that lowered ...

A 16-patient retrospective cohort found an association between finerenone initiation and lower urine albumin-to-creatinine ratio over six months, without detected ...

In a study of 70 patients with type 2 diabetes, MPO and NE mRNA expression was higher in severe albuminuric ...

A new retrospective cohort study finds that non-albuminuric diabetic kidney disease is a distinct subtype marked by heavier macrovascular disease ...

A multicenter Chinese study of 516 patients finds that corneal nerve fiber damage varies across Ahlqvist-based diabetes subtypes and is ...

A new study identifies a ceramide-gated Calhm2 calcium influx pathway, driven by Aebp1, that injures podocytes in diabetic kidney disease ...

A new study shows that the RNA demethylase FTO stabilizes EGR1 mRNA through m6A modification, activating a STING1-driven inflammatory cascade ...

A 14-year study of over 10,000 young patients at a South Indian diabetes centre shows type 2 diabetes is now ...