The Invisible Brain: Why Aging Neuroscience Must Reach the World’s Most Vulnerable Older Adults
A new Frontiers in Human Neuroscience editorial highlights how social vulnerability shapes cognitive aging and why standard research methods fail ...
Tag: dementia
Which Chronic Disease Combinations Raise Dementia Risk? New Study Points to Diabetes and Ear Disease
A community-based study of 2,458 older adults in China finds that suspected dementia is linked not just to individual chronic ...
Gut Gene RHBDF2 Emerges as Molecular Bridge Between Colitis and Brain Barrier Damage
A multi-cohort transcriptomic, genetic, and experimental study identifies the RHBDF2–ADAM17–TNFα axis as a molecular bridge linking ulcerative colitis to blood–brain ...
Nearly Half of Older Adults With Intellectual Disabilities Are Frail, Landmark Portuguese Study Finds
A first-of-its-kind Portuguese study of 234 adults with intellectual disabilities aged 45 and older finds that nearly half are frail, ...
Frontiers Retracts Study Linking Chronic Pain to Dementia Risk Over Unauthorized UK Biobank Data Use
The retraction of this cohort study highlights a dimension of research integrity that often remains invisible to readers who encounter ...
Paramedics May Flag Dementia Risk in One in Five Older Adults They Visit
A cross-sectional study of Canadian community paramedicine programs found that about one in five older adults screened with the Mini-Cog ...
Pericyte Loss and Inflamed Blood Vessel States Revealed in Brain Small Vessel Disease
A single-vessel analysis of human brain tissue shows that pericyte loss and endothelial activation are partially dissociated processes defining three ...
Hearing Loss in Aging Weakens the Brain’s Wiring, Massive Scan Study Finds
A study of more than 2,400 older adults finds that age-related hearing loss is linked to weaker structural brain connections, ...
Swallowing Trouble and Dehydration Together Raise Death Risk in Hospitalized Older Adults
A nationwide German registry study of over 1.3 million geriatric admissions finds that dehydration and dysphagia each independently raise in-hospital ...
New 40-Minute Test Tracks Cognitive Decline in Aging Dogs
Researchers have validated CANID, a repeatable and sensitive cognitive test battery that detects age-related memory and executive function changes in ...
Losing More Teeth, Losing More Memory: Study Maps Tooth Loss to Cognitive Decline
A study of nearly 7,000 Chinese older adults finds a linear dose–response relationship between remaining natural teeth and cognitive impairment, ...
Severe Vitamin D Deficiency Linked to Higher Mortality and Aging-Related Disease in Two Large Cohorts
A dual-cohort study of hundreds of thousands of Israeli and American health records links severe vitamin D deficiency to elevated ...
Dementia Care in Sub-Saharan Africa Faces a Widening Crisis as Populations Age
A new scoping review in PLOS Global Public Health reveals that Sub-Saharan Africa's health systems, technologies, and finances are unprepared ...
Landmark Genetic Analysis Places the Earliest Warning Signs of Alzheimer’s on the Disease Map
A meta-analysis of 49 studies shows that APOE ε4 carrier prevalence in subjective cognitive decline falls between cognitively normal individuals ...
Why Health and Long-Term Care Systems Are Destined to Merge
An LSE economist argues that ageing populations and failing insurance markets make the merger of health and long-term care systems ...
New Scale Captures the Hidden Role Dilemmas of Dementia Family Caregivers
Researchers at Xuzhou Medical University have developed and validated a 23-item Role Dilemma Scale that measures five distinct dimensions of ...
Dementia May Not Be a Brain Disease at All, NIH Scientists Argue
NIH researchers argue that dementia may be the late-life manifestation of a systemic failure of energy regulation rather than a ...
Crushing Pills in Nursing Homes: One in Three Manipulations May Be Unsafe
A national Italian study of 82 long-term care facilities found that nearly one in four solid oral medications is altered ...
AI Method Reads Tissue Fingerprints to Find Disease Hotspots Earlier
A new deep-learning method called VIMA converts tissue patches into numerical fingerprints and uses rigorous statistics to uncover disease-associated spatial ...
One in 100 US Adults Over 40 Reports a Dementia Diagnosis, National Survey Finds
A nationally representative US survey of more than 130,000 adults finds that 1.6 percent of people aged 40 to 85 ...
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