Copper Nanoparticles Emerge as Multifunctional Weapons in Drug Delivery and Cancer Therapy
A comprehensive review highlights how copper nanoparticles combine drug delivery, targeted tumor therapy, and the newly discovered cell death pathway ...
Tag: cuproptosis
Copper Cell Death Emerges as a Hidden Driver of Acute Kidney Injury
A new study identifies cuproptosis as a major regulated cell death pathway in ischemic acute kidney injury and shows that ...
Hidden Molecular Shield Lets Lung Cancer Cells Dodge Copper-Driven Cell Death
Researchers have mapped a USP11-IGF2BP2-ATOX1 molecular axis that shields non-small cell lung cancer cells from copper-induced cuproptosis, revealing new drug ...
Single Gene Emerges as Hidden Link Between Oxygen Starvation and Neuron Death in Parkinson’s Disease
A multi-omics study identifies the mitochondrial pyruvate carrier gene MPC2 as a causal link between hypoxia, mitochondrial energy failure, and ...
Betel Nut Chemical Shields Oral Cancer Cells From Copper-Driven Cell Death
New research shows that arecoline, the main alkaloid in betel nut, activates a ROS-NRF2-MT2A signaling axis that protects oral squamous ...
Copper Cell Death Pathway Uncovered as Driver of Blindness-Causing Retinal Injury
A new study in Cell Death Discovery shows that the copper-binding protein metallothionein 3 regulates cuproptosis in retinal ischemia–reperfusion injury ...
Iron and Copper Cell Death Pathways May Hold Key to Beating Immunotherapy Resistance
A new review in Medical Oncology argues that simultaneously inducing the iron-driven cell death ferroptosis and the copper-driven cuproptosis, tuned ...
Spermidine Shields Ovarian Cells From Copper-Triggered Cell Death, Study Finds
New research shows that the natural polyamine spermidine protects pig ovarian granulosa cells from copper overload-induced cuproptosis by suppressing miR-194a-5p ...
Multi-Omics Reveal Cuproptosis Genes in Parkinson’s
In an exciting breakthrough that could pave the way for novel therapeutic strategies in neurodegenerative disorders, researchers Zhang and Wang ...
FDX1 Drives Malignant Progression in Triple-Negative Breast Cancer
Recent advancements in cancer research have illuminated a previously underexplored area concerning the role of copper metabolism in malignancies. This ...
POPULAR NEWS
-
Case Report Tracks Multisystem Progression in Von Hippel-Lindau Syndrome Patient
-
Systematic Review Finds No Significant Glycemic Benefit From Renal Denervation in Hypertension
-
Phased Framework Proposed to Address Electronic Health Record Failures in Liberia
-
Moral Resilience and Professional Identity Mitigate Compassion Fatigue in Eldercare Interns