CpG Hypomethylation Links Thymoma Gene Expression to Myasthenia Gravis
A study in Clinical Epigenetics links promoter CpG island hypomethylation in thymoma cells to the overexpression of muscle autoantigens in ...
Tag: clinical epigenetics
New BLEND-M Method Uses Personalized DNA Methylation References for Deconvolution
A new method called BLEND-M improves DNA methylation deconvolution by using personalized reference profiles to account for individual variability.
Histone Lactylation Hypothesis Links Immune Memory to Atherosclerosis
A new hypothesis in Clinical Epigenetics proposes that histone lactylation acts as an epigenetic memory code, linking metabolic reprogramming to ...
Korean Cohort Links Homocysteine to Imprinted Methylation Domains
Researchers conducted an epigenome-wide association study (EWAS) of fasting plasma homocysteine in a large Korean cohort, identifying three imprinted genomic ...
Novel Epigenetic Regimen Shows High Remission in Adverse-Risk Acute Myeloid Leukemia
A retrospective study reports an 87.5 percent complete remission rate with the novel CACAG-VEN regimen in newly diagnosed ELN 2022 ...
Comprehensive Study Clarifies Long-Term Features of Rare Kagami-Ogata Syndrome
A comprehensive study of 67 Japanese patients with molecularly confirmed Kagami-Ogata syndrome clarifies the rare imprinting disorder's long-term growth, respiratory, ...
Review Links Ubiquitination and Acylation in Cancer Resistance
A 2026 review in Clinical Epigenetics examines how ubiquitination and acylation modifications interact to drive cancer drug resistance and identifies ...
Researchers Outline Key Considerations for Designing CRISPR-Based Epigenetic Editing Experiments
A review in Clinical Epigenetics outlines experimental considerations and unresolved challenges for designing CRISPR-dCas9 epigenetic editing studies.
Perceived stress linked to blood DNA methylation and epigenetic aging signs in young women
A study of 195 young healthy Chinese women found that higher perceived stress was associated with four blood DNA methylation ...
EBV-driven lymphoproliferative disorders show disrupted DNA methylation patterns
A new review links EBV-driven lymphoproliferative disorders to disrupted DNA methylation and outlines emerging epigenetic treatment strategies.
One Blood Test, Two Answers: Nanopore Sequencing Reads Genes and Methylation Together
Nanopore long-read sequencing that simultaneously reads genetic variants and DNA methylation resolved three difficult KMT2B-related dystonia diagnoses, confirming one uncertain ...
Organ ageing clocks show direction-dependent genetic links with disease
A UK Biobank genetic study finds organ-specific biological age gaps show heterogeneous, direction-dependent genetic relationships with age-related diseases.
Blood lipid–linked DNA methylation patterns replicate in Korean adults and tie to epigenetic aging
An epigenome-wide study of 1,527 Korean adults confirms core lipid–methylation loci and links ABCG1 methylation to the association between accelerated ...
Epigenetics Beyond the Clinic: A New Journal Charts the Field’s Next Frontier
The launch of the open access journal Epigenetics Communications marks a push to understand dynamic epigenetic networks, publish negative results ...
Innovative Urine Test Detects Tumor DNA to Identify Bladder Cancer
In a groundbreaking advancement poised to revolutionize non-invasive cancer diagnostics, researchers at the University of Birmingham’s Bladder Cancer Research Centre ...
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