Tag: Chemotherapy Resistance

A bioinformatics analysis indicates that high TLN1 expression correlates with poorer survival outcomes in cervical cancer patients receiving cisplatin chemotherapy.

A review analyzes how glioblastoma stem cells and the perivascular niche remodel the blood-brain barrier into a persistent obstacle to ...

A review highlights how targeting Survivin in breast cancer requires overcoming delivery and resistance barriers through synergistic combination therapies.

A Foshan-based team identifies Ruminococcus lactaris as a gut bacterium that drives breast cancer progression and chemotherapy resistance via a ...

A new BMC Cancer study shows that high-dose sodium butyrate suppresses HDAC4 and TUG1 to reverse oxaliplatin resistance in colorectal ...

Chemotherapy activates cGAS–STING in head and neck cancer cells, driving TNF release, IKKβ-mediated ATG9A S654 phosphorylation and autophagy that promotes ...

Elevated LINC00626 enhances STAT3 Tyr705 phosphorylation and CCL20 expression, helping hepatocellular carcinoma cells tolerate oxaliplatin in cell and xenograft models.

Researchers in Barcelona report that a six-gene activity score, anchored by the Polycomb factor PHF19, divides acute myeloid leukaemia patients ...

A 2026 review finds that miR-142-3p generally suppresses tumor-cell growth and improves drug response inside cancer cells, while its extracellular-vesicle ...

A retrospective Chinese cohort study found that perineural invasion in resected colorectal cancer was independently associated with distant metastasis and ...

A new study identifies RRM2 as a gene that connects nucleotide metabolism and SREBP1/FASN-driven lipid remodeling to gemcitabine resistance in ...

New research shows the plant polyphenol ellagic acid sensitizes wild-type TP53 colorectal tumors to oxaliplatin by suppressing ATM signaling and ...

A landmark single-cell and spatial transcriptomics study of 62 pancreatic tumors shows that genetically distinct clones within each cancer drive ...

Patient-derived organoid and xenograft models reveal that a collagen I-rich tumor matrix activates TGFβ signaling and LTBP2 expression, priming colorectal ...

A newly reported leukemia case carrying both the rare DEK::CAN fusion gene and WT1 overexpression reveals how genetic synergy and ...

A systematic review of 21 preclinical studies finds that curcumin and its nanoformulations modulate key cancer signaling pathways and enhance ...

New research shows that BH3 mimetic drugs targeting antiapoptotic Bcl-2 family proteins can sensitize bladder cancer cells and patient-derived tumor ...

A new review maps how cancer-associated fibroblasts exclude immune cells from osteosarcoma tumors and outlines the therapeutic strategies that could ...

A new review reveals how the long non-coding RNA MIR99AHG acts as a multifunctional host gene and regulatory hub whose ...

In a groundbreaking advancement for acute myeloid leukemia (AML) treatment, researchers have uncovered a promising combination therapy that holds the ...