Tag: CD8+ T cells

A three-dimensional fibrin hydrogel system preserving freshly isolated human bone marrow mononuclear cells revealed marked shifts in vascular and immune ...

A computational study using machine learning identified two palmitoylation-related genes as prognostic biomarkers in lung cancer and nominated montelukast sodium ...

In a randomized phase 2 trial, an off-the-shelf vaccine directed against mutated KRAS generated strong T-cell responses in nearly all ...

A study in mice reveals that host vascular aging, rather than the intrinsic age of T cells, drives age-related increases ...

Elevated HHLA2 expression in esophageal squamous cell carcinoma tissues and immune cell subsets predicts significantly poorer overall survival.

Researchers developed FlAsH-ID, a photocatalytic proximity labeling method using a six-amino-acid peptide tag that maps protein interactomes in living cells ...

Hyperthermia enhances anti-PD-L1 immunotherapy efficacy in preclinical non-small cell lung cancer models by upregulating PD-L1 expression through activation of the ...

In a murine model of pancreatic adenocarcinoma, ultrasound histotripsy and radiotherapy induced local tumor control while activating distinct myeloid and ...

Researchers have demonstrated that the RNA methyltransferase subunit RBM15 drives immune evasion in non-small cell lung cancer cell models by ...

An injectable hydrogel triggered by abdominal sodium delivers engineered Salmonella to shrink melanoma tumours in mice while curbing weight loss ...

A retrospective cohort study at Peking Union Medical College Hospital identifies low serum albumin, reduced immunoglobulin G, and prior corticosteroid ...

Dynamic increases in peripheral blood CX3CR1-positive CD8-positive T cells during pembrolizumab-containing neoadjuvant chemotherapy were associated with pathological response in patients ...

A phase 2 clinical trial found that combining regorafenib, chemotherapy, and nivolumab was safe and remodeled the tumor microenvironment in ...

Integrating single-cell and spatial transcriptomics reveals five pancreatic cancer innervation subtypes linked to patient prognosis and immunotherapy resistance.

Researchers demonstrated that molecular contrast-enhanced ultrasound using VEGFR2-targeted microbubbles detects early vascular and immunological changes during dual checkpoint immunotherapy in ...

A machine learning model identified a five-gene immune evasion signature that stratifies bladder cancer survival and associates with immunotherapy response ...

A randomized trial found that combining Yiqi Jiedu granules with anti-PD-1 immunotherapy significantly prolonged overall survival in patients with PD-L1-high ...

An eight-gene stress granule signature stratifies survival outcomes and characterizes immune microenvironments in esophageal squamous cell carcinoma.

A translational study reveals that higher predicted donor-recipient HLA epitope mismatch associates with distinct innate immune cell configurations in clinically ...

A comprehensive review examines how lactate accumulation orchestrates acute metabolic suppression, immune lineage remodeling, and candidate epigenetic state fixation across ...