Preclinical multi-omics research shows toddalolactone improves cardiac function and metabolic status in diabetic cardiomyopathy models by modulating PKCĪ± signaling.
Knockdown of TRAF1 in aging mice reduced cardiac inflammation, attenuated hypertrophy, and improved diastolic function by blocking mitochondrial DNA release.
Knockdown of LOX-1 ameliorated ethanol-induced cardiac hypertrophy and apoptosis in rodent models by restoring p38MAPK-mediated autophagy.
A study reveals that defective chaperone-mediated autophagy stabilizes RAB10 and drives excessive glucose uptake into cardiac and skeletal muscles in ...
A study in Cell Biology and Toxicology reports that H3K18 lactylation promotes ALKBH5 transcription, which stabilises ATF6 mRNA through m6A ...
A new study combining network pharmacology, molecular docking, and H9C2 cell experiments found that low-dose Ponatinib significantly reduced high-salt-induced hypertrophy ...
A low-valine diet reduced pathological cardiac hypertrophy and improved cardiac function in hypertensive male rodents by limiting LONP1-mediated degradation of ...
A minireview reports that cardiomyocyte-specific loss of the Bmal1 clock gene increases cardiac growth hormone sensitivity in mice, raising a ...
Astragaloside IV reduces pathological cardiac hypertrophy and suppresses ferroptosis in separate models, but direct experiments are needed to establish whether ...
New research in PLOS Genetics identifies the ZBED6āMEOX1āERK1/2 axis as a key regulator of pathological cardiac hypertrophy through impaired autophagy.
Researchers in the field of cardiovascular biology have recently unveiled a captivating study relating to the protein LRRC8A, which is ...
