Tag: Cancer Immunology

A longitudinal immune monitoring study showed that combining tinostamustine with nivolumab was linked to preserved adaptive immune competence and antigen-specific ...

Pre-treatment gene signatures combining immune activity and tumor-intrinsic markers such as SLC7A5 and SOX2 are associated with response and resistance ...

Genetic screens in aged mice identify Dusp5 and Zfp219 as regulators whose deletion can restore anti-tumor T cell function, with ...

Researchers report that SERPINA3 acts as a soluble SIRPα ligand that suppresses immune cells, easing inflammatory disease models while helping ...

A new review describes how tumors reprogram Schwann cells into states linked to perineural invasion, matrix remodeling and altered immune-cell ...

A Dana-Farber-led Immunity study shows that p53-mutant cancers can evade T-cell detection through several mechanisms, while laboratory ERAP1 inhibition restores ...

A preclinical study found that SIRPα signaling inside triple-negative breast cancer cells promoted mitochondrial fission, motility, immune tolerance and brain ...

A mouse study found that removing ANKRD11 enhanced CD8+ T-cell activity against chronic hepatitis B virus infection and cancer, but ...

A retrospective cohort study linked enteral nutrition within 24 hours of gastrectomy for gastric cancer with better preservation of selected ...

A preclinical study reports that the IL-13E13Y-based T-cell engager 313TE linked IL-13Rα2-positive tumor cells to T cells, promoting receptor-dependent killing ...

A first small clinical study found encouraging tumor control, symptom relief and tolerability with minibeam radiotherapy in 36 patients with ...

A million-cell atlas identifies distinct human neutrophil states linked to infection, cancer, sex, metabolic health and mortality, while highlighting the ...

A new study reveals that PRKDC, a gene known for DNA repair, drives immune evasion in hepatocellular carcinoma by pushing ...

A new review explains why BCG immunotherapy fails in some bladder cancer patients and outlines emerging combination strategies designed to ...

WEHI researchers have discovered that gamma delta T cells can recognise and kill small cell lung cancer, and that two ...

A new Nature Aging study from Mass General Brigham shows that male and female immune systems age differently, with earlier ...

A Taiwanese preliminary study found that following a short course of immune checkpoint inhibitors with infusions of tumor-primed dendritic cells ...

In a groundbreaking study, a team of researchers led by Hao et al. presents a remarkable investigation into the heterogeneity ...