Oncotarget: TERT and its binding protein: overexpression of GABPA/B in gliomas
This Oncotarget study confirms the upregulation of TERT in primary glioblastomas while all GABP proteins rise with the malignancy of ...
Tag: cancer
Oncotarget: Replication-stress sensitivity in breast cancer cells
Taken together these Oncotarget findings show that the CTD and OD domains of mtp53 R273H play critical roles in mutant ...
Comprehensive clinical sequencing opens door to the promise of precision medicine
St. Jude Children's Research Hospital study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to better ...
New organ-on-a-chip finds crucial interaction between blood, ovarian cancer tumors
Team identifies crucial interaction between platelets and tumors for the first timeCredit: Texas A&M Engineering In the evolving field of ...
Novel imaging agent identifies biomarker for iron-targeted cancer therapies
Credit: Image created by Evans, Renslo et al. University of California San Francisco. Reston, VA--A new radiotracer that detects iron ...
Research identifies potential role of ‘junk DNA’ sequence in aging, cancer
Credit: Photo by Cori Kogan, WSU Health Sciences Spokane The human body is essentially made up of trillions of living ...
Phase two CD19-antibody-drug conjugate trial demonstrates promise for aggressive lymphoma
MUSC Hollings Cancer Center part of promising clinical trial for aggressive lymphomaCredit: MUSC Hollings Emma C. Vought MUSC Hollings Cancer ...
Chemotherapy can induce mutations that lead to pediatric leukemia relapse
A collaboration led by St. Jude Children's Research Hospital, Shanghai Children's Medical Center and others revealed how thiopurines produce mutations ...
Oncotarget: Fgr and Numb in retinoic differentiation and G0 arrest of non-APL AML cells
In sum the Oncotarget data support a paradigm where signaling molecules bound to a Numb scaffold in a signalsome are ...
Studies find combination chemotherapy beneficial and cost-effective in sub-Saharan Africa
Credit: UNC School of Medicine CHAPEL HILL, North Carolina--Researchers at the UNC Lineberger Comprehensive Cancer Center demonstrated in a clinical ...
Advanced bladder cancers respond to immunotherapy regardless of gene mutation status
Credit: UNC LIneberge Comprehensive Cancer Center CHAPEL HILL, North Carolina--A new study has demonstrated that patients with advanced bladder cancers ...
Study on chromosomal rearrangements in yeast reveals potential avenue for cancer therapy
Researchers from Osaka University uncover a mechanism by which chromosomal rearrangements occur, with implications for novel cancer therapiesCredit: Osaka University ...
Investigational magnetic device shrinks glioblastoma in first-in-world human test
Credit: Houston Methodist Houston Methodist Neurological Institute researchers from the department of neurosurgery shrunk a deadly glioblastoma tumor by more ...
Cardio-cerebrovascular disease history complicates hematopoietic cell transplant outcomes
Researchers find pre-transplant cardiovascular diseases indirectly affect mortality and survival through increased post-transplant disease occurrenceCredit: Chinese Medical Journal Hematopoietic cell ...