Geometrical Gene Signatures Accurately Predict Cancer Treatment Response in Clinical Trials
A study using Phase III renal cell carcinoma trial data found that geometry-based gene-expression signatures predicted patient response to combination ...
A study using Phase III renal cell carcinoma trial data found that geometry-based gene-expression signatures predicted patient response to combination ...
A bibliometric analysis of 1,175 articles published between 2005 and 2026 identifies China as the leading contributor to endometriosis epigenetics ...
A 2026 letter to the editor highlights that five-year RESCUEicp data shows no benefit for decompressive craniectomy in patients over ...
A computational transcriptomics and machine learning study identified four shared regulatory genes and two candidate repurposed drugs linking type 2 ...
A new AI framework combines retinal imaging with clinical vitals to assess cardiovascular disease risk, showing improved performance in women ...
Researchers demonstrated that TSPO-targeted PET imaging with DPA-714 selectively maps early inflammatory muscle remodeling downstream of peripheral nerve crush in ...
A retrospective study of 485 patients found that combining the lymphocyte-to-monocyte ratio with circulating Epstein–Barr virus DNA improved prognostic risk ...
A review in Molecular Biology Reports maps diagnostic and prognostic biomarkers for pediatric cerebral malaria to specific molecular pathophysiological steps, ...
Pediatric acute respiratory distress syndrome research is increasingly leveraging multi-biomarker panels, statistical subphenotyping, and dynamic temporal trajectories to guide targeted ...
A cross-sectional study found that elevated circulating activin A concentrations are associated with increased liver stiffness and greater disease severity ...
A systematic review of nine studies found that transient elastography and combined biomarker-imaging approaches show promising accuracy for detecting cirrhosis ...
A proteomic analysis of bladder biopsies identifies baseline proteins and immune pathways associated with patient response to hyperbaric oxygen therapy ...
A simulation study indicates joint models remain robust to missing markers, but elevated biomarker measurement error introduces bias.
A retrospective study of 16 children with stage 4 neuroblastoma found that elevated plasma catecholamines were associated with a higher ...
A retrospective cross-sectional study finds that GBP2 mRNA expression decreases stepwise with increasing COVID-19 severity, while GBP5 shows a weaker, ...
A retrospective study of 517 patients found that mid-treatment MRI response strongly predicts pathologic complete response in triple-negative breast cancer, ...
A retrospective study in European Radiology Experimental shows that synthetic MRI provides reproducible quantitative biomarkers for differentiating active and inactive ...
A study of UK Biobank data revealed that age, waist-hip ratio, and handgrip strength predict hundreds of diverse health outcomes ...
A cross-sectional study identifies distinct peripheral microRNA signatures in blood associated with pharmacoresistance in temporal lobe epilepsy, with miR-128 and ...
A new metabolomics-based diagnostic model using machine learning shows high accuracy in detecting radiation-induced heart disease through plasma biomarkers.
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